PMID- 11528310
OWN - NLM
STAT- MEDLINE
DCOM- 20011011
LR  - 20191105
IS  - 1095-0680 (Print)
IS  - 1095-0680 (Linking)
VI  - 17
IP  - 3
DP  - 2001 Sep
TI  - Factors influencing treatment frequency of continuation ECT in schizophrenia.
PG  - 190-4
AB  - Although continuation and maintenance electroconvulsive therapy (C-ECT and M-ECT) 
      have been used since 1943, no studies reported data that might help guide the 
      selection of C-ECT frequency. This two-phase study was conducted in 32 chronic 
      schizophrenic patients, with history of prior responsiveness to ECT to determine 
      clinical variables associated with treatment frequency of C-ECT. After acute 
      combination treatment with ECT and neuroleptics (Phase I), all patients received 
      weekly ECT during the first 4 weeks of C-ECT (Phase II). They were then assigned 
      to receive either weekly (n = 8) or biweekly (n = 24) ECT, depending on the 
      history of their prior responsiveness to C-/M-ECT and their Brief Psychiatric 
      Rating Scale (BPRS) scores. At the third month, patients with biweekly ECT were 
      assigned to receive either biweekly (n = 17) or triweekly ECT (n = 7) following 
      the same criteria. The duration of Phase II was 6 months. Onset of illness, 
      numbers of admission, educational level, duration of trials of the previously 
      failed neuroleptics, BPRS scores, and percentage of reductions in BPRS scores at 
      the end of Phase I, Global Assessment of Functioning (GAF) scores at the end of 
      Phase I, Mini-Mental State Exam (MMSE) scores at Phase I entry and Phase I end, 
      and GAF and MMSE scores during the first month of Phase II showed a 
      differentiation between patients having weekly treatment versus biweekly 
      treatment. Whereas a history of previously failed flupenthixol treatment, dosage 
      of flupenthixol used in this study, and MMSE scores at the end of Phase I and 
      during the first month of Phase II showed a differentiation between patients 
      having biweekly C-ECT versus triweekly C-ECT. Our results suggest that the better 
      the prognostic factors for each patient, the longer the frequency of C-ECT.
FAU - Chanpattana, W
AU  - Chanpattana W
AD  - Department of Psychiatry, Srinakharinwirot University, Dusit, Bangkok, Thailand. 
      worch@loxinfo.th
FAU - Chakrabhand, M L
AU  - Chakrabhand ML
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - J ECT
JT  - The journal of ECT
JID - 9808943
SB  - IM
MH  - Adult
MH  - Chronic Disease
MH  - *Electroconvulsive Therapy
MH  - Female
MH  - Humans
MH  - Male
MH  - Prognosis
MH  - Recurrence
MH  - Risk Factors
MH  - Schizophrenia/*therapy
MH  - Time Factors
MH  - Treatment Outcome
EDAT- 2001/08/31 10:00
MHDA- 2001/10/12 10:01
CRDT- 2001/08/31 10:00
PHST- 2001/08/31 10:00 [pubmed]
PHST- 2001/10/12 10:01 [medline]
PHST- 2001/08/31 10:00 [entrez]
AID - 10.1097/00124509-200109000-00008 [doi]
PST - ppublish
SO  - J ECT. 2001 Sep;17(3):190-4. doi: 10.1097/00124509-200109000-00008.