PMID- 11530333
OWN - NLM
STAT- MEDLINE
DCOM- 20011101
LR  - 20191105
IS  - 1471-4914 (Print)
IS  - 1471-4914 (Linking)
VI  - 7
IP  - 9
DP  - 2001 Sep
TI  - Processing and presentation of antigens by dendritic cells: implications for 
      vaccines.
PG  - 388-94
AB  - Dendritic cells (DCs) are potent antigen-presenting cells that are specialized in 
      initiation of T-cell immunity. DCs induce promising anti-tumor T-cell and 
      clinical responses, apparently without significant toxicity. Under certain 
      conditions, DCs even silence T-cell immune responses in vivo. This dual capacity 
      to modulate the immune system uniquely positions DCs for the treatment of 
      autoimmunity, cancer and chronic viral infections.
FAU - Bhardwaj, N
AU  - Bhardwaj N
AD  - The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA. 
      bhardwn@rockvax.rockefeller.edu
LA  - eng
GR  - AI 44628/AI/NIAID NIH HHS/United States
GR  - CA 84512/CA/NCI NIH HHS/United States
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, P.H.S.
PT  - Review
PL  - England
TA  - Trends Mol Med
JT  - Trends in molecular medicine
JID - 100966035
RN  - 0 (Adjuvants, Immunologic)
RN  - 0 (Antigens)
RN  - 0 (Vaccines)
SB  - IM
MH  - Adjuvants, Immunologic
MH  - Animals
MH  - Antigen Presentation/*immunology
MH  - Antigens/immunology
MH  - CD4-Positive T-Lymphocytes/immunology
MH  - CD8-Positive T-Lymphocytes/immunology
MH  - Dendritic Cells/cytology/*immunology
MH  - Humans
MH  - Immunotherapy/methods
MH  - Killer Cells, Natural/immunology
MH  - Models, Immunological
MH  - Vaccines/adverse effects/*immunology
RF  - 72
EDAT- 2001/09/01 10:00
MHDA- 2001/11/03 10:01
CRDT- 2001/09/01 10:00
PHST- 2001/09/01 10:00 [pubmed]
PHST- 2001/11/03 10:01 [medline]
PHST- 2001/09/01 10:00 [entrez]
AID - S1471-4914(01)02101-3 [pii]
AID - 10.1016/s1471-4914(01)02101-3 [doi]
PST - ppublish
SO  - Trends Mol Med. 2001 Sep;7(9):388-94. doi: 10.1016/s1471-4914(01)02101-3.