PMID- 11548903
OWN - NLM
STAT- MEDLINE
DCOM- 20020111
LR  - 20190915
IS  - 0937-4477 (Print)
IS  - 0937-4477 (Linking)
VI  - 258
IP  - 5
DP  - 2001 Jul
TI  - S-100 protein-positive dendritic cells and CD34-positive dendritic interstitial 
      cells in palatine tonsils.
PG  - 243-5
AB  - Dendritic cells (DCs) are effective antigen-presenting cells and have been shown 
      to mature from precursor CD34-positive stromal cells (dendritic interstitial 
      cells, DICs) or monocytes. To gain insight into the local immune response in 
      human tonsils, we investigated immunohistochemically the presence of DCs and DICs 
      in 17 non-hyperplastic and 13 hyperplastic tonsils. Dense infiltrates of 
      S-100-positive DCs were noted in the majority of hyperplastic tonsils, while 
      there were fewer in non-hyperplastic tonsils. DICs were noted specifically at the 
      periphery in the dense hemi-capsule cap that separates the tonsil from the 
      underlying muscle. In addition, their small number suggests that the accumulation 
      of S-100 dendritic cells in hyperplastic palatine tonsils is achieved through 
      migration from other sites rather than through maturation from precursors 
      locally.
FAU - Papadas, T
AU  - Papadas T
AD  - Department of Oto-Rhino-Laryngology, University of Patras Medical School, 
      Regional University of Patras, Greece.
FAU - Batistatou, A
AU  - Batistatou A
FAU - Ravazoula, P
AU  - Ravazoula P
FAU - Zolota, V
AU  - Zolota V
FAU - Goumas, P
AU  - Goumas P
LA  - eng
PT  - Journal Article
PL  - Germany
TA  - Eur Arch Otorhinolaryngol
JT  - European archives of oto-rhino-laryngology : official journal of the European 
      Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the 
      German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
JID - 9002937
RN  - 0 (Antigens, CD34)
RN  - 0 (S100 Proteins)
SB  - IM
MH  - Adult
MH  - Antigens, CD34/*analysis
MH  - Chronic Disease
MH  - Dendritic Cells/*immunology
MH  - Female
MH  - Humans
MH  - Hyperplasia/immunology/pathology/surgery
MH  - Immunohistochemistry
MH  - Male
MH  - Palatine Tonsil/*immunology/*pathology/surgery
MH  - Recurrence
MH  - S100 Proteins/*analysis
MH  - Stromal Cells/immunology
MH  - Tonsillitis/*immunology/*pathology/surgery
EDAT- 2001/09/11 10:00
MHDA- 2002/01/12 10:01
CRDT- 2001/09/11 10:00
PHST- 2001/09/11 10:00 [pubmed]
PHST- 2002/01/12 10:01 [medline]
PHST- 2001/09/11 10:00 [entrez]
AID - 10.1007/s004050100355 [doi]
PST - ppublish
SO  - Eur Arch Otorhinolaryngol. 2001 Jul;258(5):243-5. doi: 10.1007/s004050100355.