PMID- 11564375
OWN - NLM
STAT- MEDLINE
DCOM- 20020212
LR  - 20191105
IS  - 1523-3774 (Print)
IS  - 1523-3774 (Linking)
VI  - 3
IP  - 5
DP  - 2001 Oct
TI  - Insights into the Role of Infection in the Spondyloarthropathies.
PG  - 428-34
AB  - Certain infections play an important role in the pathogenesis of the human 
      leukocyte antigen (HLA)-B27-associated reactive arthritis. Whether infections 
      play a role in other forms of spondyloarthropathies is not as clear. The role of 
      HLA-B27 as an antigen-presenting molecule is important in the pathogenesis of 
      these diseases. Recent evidence has been obtained indicating that this molecule 
      may have other functions unrelated to antigen-presentation in the interaction of 
      reactive arthritis-triggering microbes and host. This paper reviews the recent 
      studies on the role of infection in the spondyloarthropathies.
FAU - Liu, Y
AU  - Liu Y
AD  - National Public Health Institute, Department in Turku, Kiinamyllynkatu 13, 
      FIN-20520 Turku, Finland. yiliu@utu.fi
FAU - Penttinen, M A
AU  - Penttinen MA
FAU - Granfors, K
AU  - Granfors K
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Curr Rheumatol Rep
JT  - Current rheumatology reports
JID - 100888970
RN  - 0 (Biomarkers)
RN  - 0 (HLA-B27 Antigen)
SB  - IM
MH  - Animals
MH  - Arthritis, Reactive/immunology/physiopathology
MH  - Bacterial Infections/*immunology/*physiopathology
MH  - Biomarkers/analysis
MH  - Female
MH  - HLA-B27 Antigen/*immunology
MH  - Humans
MH  - Male
MH  - Mice
MH  - Prognosis
MH  - Risk Assessment
MH  - Risk Factors
MH  - Sensitivity and Specificity
MH  - Spondylarthropathies/*immunology/*physiopathology
MH  - Spondylitis, Ankylosing/immunology/physiopathology
RF  - 80
EDAT- 2001/09/21 10:00
MHDA- 2002/02/13 10:01
CRDT- 2001/09/21 10:00
PHST- 2001/09/21 10:00 [pubmed]
PHST- 2002/02/13 10:01 [medline]
PHST- 2001/09/21 10:00 [entrez]
AID - 10.1007/s11926-996-0014-6 [doi]
PST - ppublish
SO  - Curr Rheumatol Rep. 2001 Oct;3(5):428-34. doi: 10.1007/s11926-996-0014-6.