PMID- 11570190
OWN - NLM
STAT- MEDLINE
DCOM- 20020131
LR  - 20061115
IS  - 0005-9366 (Print)
IS  - 0005-9366 (Linking)
VI  - 114
IP  - 9-10
DP  - 2001 Sep-Oct
TI  - Sequence polymorphism of the Salmonella plasmid virulence factor D (SpvD) in 
      Salmonella enterica isolates of animal origin.
PG  - 404-8
AB  - The nucleotide sequence encoding the Salmonella plasmid virulence factor D (SpvD) 
      was determined in 17 Salmonella strains that were different in O and H antigen 
      patterns, animal host and geographical origin, and year of isolation. Nucleotide 
      sequence comparison revealed the existence of at least nine spvD alleles 
      resulting in 8 SpvD protein variants although the nucleotide sequences were 
      highly similar (identity 98.8-100%). The spvD gene products differed from each 
      other in up to 4 amino acid residues only with the exception of the 
      carboxy-terminally truncated SpvD variant of one S. Gallinarum field isolate. The 
      highly conserved primary structure of SpvD in epidemiologically relevant 
      salmonellae suggests that this virulence factor is a promising antigen candidate 
      for diagnostic purposes (i.e. antibody detection in infected animals) but also 
      for immunoprophylaxis in farm animal species.
FAU - Bauerfeind, R
AU  - Bauerfeind R
AD  - Institute for Hygiene and Infectious Diseases of Animals, Justus Liebig 
      University Giessen, Germany. rolf.bauerfeind@vetmed.uni-giessen.de
FAU - Barth, S
AU  - Barth S
FAU - Weiss, R
AU  - Weiss R
FAU - Baljer, G
AU  - Baljer G
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Germany
TA  - Berl Munch Tierarztl Wochenschr
JT  - Berliner und Munchener tierarztliche Wochenschrift
JID - 0003163
RN  - 0 (Antigens, Bacterial)
RN  - 0 (Bacterial Proteins)
RN  - 0 (DNA Primers)
RN  - 0 (DNA, Bacterial)
RN  - 0 (SpvD protein, Salmonella enterica)
RN  - 0 (Virulence Factors)
RN  - EC 2.4.2.- (ADP Ribose Transferases)
SB  - IM
MH  - ADP Ribose Transferases/chemistry/*genetics
MH  - Amino Acid Sequence
MH  - Animals
MH  - *Antigens, Bacterial
MH  - *Bacterial Proteins
MH  - Base Sequence
MH  - DNA Primers
MH  - DNA, Bacterial/analysis/chemistry
MH  - Genes, Bacterial
MH  - Molecular Sequence Data
MH  - Phylogeny
MH  - Plasmids
MH  - *Polymorphism, Genetic
MH  - Salmonella/classification/*genetics/pathogenicity
MH  - Salmonella Infections, Animal/*genetics
MH  - Virulence
MH  - *Virulence Factors
EDAT- 2001/09/26 10:00
MHDA- 2002/02/01 10:01
CRDT- 2001/09/26 10:00
PHST- 2001/09/26 10:00 [pubmed]
PHST- 2002/02/01 10:01 [medline]
PHST- 2001/09/26 10:00 [entrez]
PST - ppublish
SO  - Berl Munch Tierarztl Wochenschr. 2001 Sep-Oct;114(9-10):404-8.