PMID- 11579647
OWN - NLM
STAT- MEDLINE
DCOM- 20020221
LR  - 20191210
IS  - 0254-9395 (Print)
IS  - 0254-9395 (Linking)
VI  - 73
IP  - 2
DP  - 2001 Apr-Jun
TI  - Lot quality assurance sampling (LQAS) for monitoring leprosy elimination in an 
      endemic district in Tamilnadu.
PG  - 111-9
AB  - This paper examines whether the health administration can use lot quality 
      assurance sampling (LQAS) for identifying high prevalence areas for leprosy for 
      initiating necessary corrective measures. The null hypothesis was that leprosy 
      prevalence in the district was at or above ten per 10,000 and the alternative 
      hypothesis was that it was at or below five per 10,000. A total of 25,500 
      individuals were to be examined with 17 as an acceptable maximum number of cases 
      (critical value). Two-stage cluster sample design was adopted. The sample size 
      need not be escalated as the estimated design effect was 1. During the first 
      phase, the survey covered a population of 4,837 individuals out of whom 4,329 
      (89.5%) were examined. Thirty-five cases were detected and this number far 
      exceeded the critical value. It was concluded that leprosy prevalence in the 
      district should be regarded as having prevalence of more than ten per 10,000 and 
      further examination of the population in the sample was discontinued. LQAS may be 
      used as a tool by which one can identify high prevalence districts and target 
      them for necessary strengthening of the programme. It may also be considered for 
      certifying elimination achievement for a given area.
FAU - Murthy, B N
AU  - Murthy BN
AD  - National Institute of Epidemiology, Mayor V.R. Ramanathan Road, Chetpet, Chennai 
      600 031.
FAU - Subbiah, M
AU  - Subbiah M
FAU - Boopathi, K
AU  - Boopathi K
FAU - Ramakrishnan, R
AU  - Ramakrishnan R
FAU - Gupte, M D
AU  - Gupte MD
LA  - eng
PT  - Evaluation Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - India
TA  - Indian J Lepr
JT  - Indian journal of leprosy
JID - 8409173
SB  - IM
MH  - Cluster Analysis
MH  - Endemic Diseases/prevention & control
MH  - *Epidemiologic Methods
MH  - Humans
MH  - India/epidemiology
MH  - Leprosy/*epidemiology/*prevention & control
MH  - Prevalence
MH  - Quality Assurance, Health Care/*methods
MH  - Rural Population
MH  - Sampling Studies
MH  - Urban Population
EDAT- 2001/10/03 10:00
MHDA- 2002/02/22 10:01
CRDT- 2001/10/03 10:00
PHST- 2001/10/03 10:00 [pubmed]
PHST- 2002/02/22 10:01 [medline]
PHST- 2001/10/03 10:00 [entrez]
PST - ppublish
SO  - Indian J Lepr. 2001 Apr-Jun;73(2):111-9.