PMID- 11582994
OWN - NLM
STAT- MEDLINE
DCOM- 20011204
LR  - 20201208
IS  - 0043-5341 (Print)
IS  - 0043-5341 (Linking)
VI  - 151
IP  - 13-14
DP  - 2001
TI  - [Healing peptic ulcer disease with therapy of Helicobacter pylori infection--an 
      overview].
PG  - 300-8
AB  - Over the last 15 years several new aspects in the pathogenesis and basic changes 
      in therapeutic strategies for healing of peptic ulcers have been introduced. The 
      discovery of Helicobacter pylori, the possibility of treatment of the infection 
      and consecutive healing of peptic ulcer disease have changed the understanding of 
      the pathophysiology of the peptic ulcer disease. Most gastric or duodenal ulcers 
      are based on Helicobacter pylori infection. Newer therapeutic strategies to cure 
      Helicobacter pylori infection consist of proton pump inhibitor (PPI) based triple 
      therapy, containing in addition two antibiotics chosen from clarithromycin, 
      amoxicillin and metronidazole, administered over 7 days. The other main cause of 
      gastroduodenal ulcers are non-steroidal antirheumatic drugs or aspirin intake. 
      PPI are therapeutic strategies of choice for treatment of such lesions. Main 
      topics of this overview are the principles and the therapeutic proceeding in the 
      management of Helicobacter pylori-associated peptic ulcer disease. The 
      differences between duodenal and gastric ulcer are especially dealt with.
FAU - Leodolter, A
AU  - Leodolter A
AD  - Klinik fur Gastroenterologie, Hepatologie und Infektiologie, 
      Otto-von-Guericke-Universitat, Leipziger Strasse 44, D-39120 Magdeburg, 
      Deutschland.
FAU - Peitz, U
AU  - Peitz U
FAU - Malfertheiner, P
AU  - Malfertheiner P
LA  - ger
PT  - Journal Article
PT  - Review
TT  - Die Heilung der peptischen Ulkuskrankheit durch Therapie der 
      Helicobacter-pylori-Infektion--eine Ubersicht.
PL  - Austria
TA  - Wien Med Wochenschr
JT  - Wiener medizinische Wochenschrift (1946)
JID - 8708475
RN  - 0 (Anti-Bacterial Agents)
RN  - 0 (Anti-Ulcer Agents)
RN  - 0 (Proton Pump Inhibitors)
SB  - IM
MH  - *Anti-Bacterial Agents
MH  - Anti-Ulcer Agents/adverse effects/*therapeutic use
MH  - Clinical Trials as Topic
MH  - Drug Therapy, Combination/adverse effects/*therapeutic use
MH  - Helicobacter Infections/*drug therapy
MH  - *Helicobacter pylori/drug effects
MH  - Humans
MH  - Peptic Ulcer/*drug therapy
MH  - *Proton Pump Inhibitors
MH  - Recurrence
RF  - 93
EDAT- 2001/10/05 10:00
MHDA- 2002/01/05 10:01
CRDT- 2001/10/05 10:00
PHST- 2001/10/05 10:00 [pubmed]
PHST- 2002/01/05 10:01 [medline]
PHST- 2001/10/05 10:00 [entrez]
PST - ppublish
SO  - Wien Med Wochenschr. 2001;151(13-14):300-8.