PMID- 11599352
OWN - NLM
STAT- MEDLINE
DCOM- 20011204
LR  - 20171116
IS  - 1001-5302 (Print)
IS  - 1001-5302 (Linking)
VI  - 23
IP  - 11
DP  - 1998 Nov
TI  - [Inhibition of beta-amyloid precursor protein gene expression by haifengteng].
PG  - 691-3, inside back cover
AB  - OBJECTIVE: To study the inhibition of beta-amyloid precursor protein(beta-APP) 
      gene expression by Haifengteng. METHOD: Northern Blot analysis was used to 
      investigate the level of beta-APP mRNA, and cell viability, LDH-release and 
      colony formation assay were used to study the effect of Hairengteng of neurons. 
      RESULT: Haifengteng inhibited the expression of beta-APP gene selectively without 
      causing cell injuries. CONCLUSION: beta-APP is closely related to Alzheimer's 
      disease. The findings in this study could be a basis for Haifengteng to have 
      therapeutic potentials in treating Alzheimer's disease.
FAU - Han, E
AU  - Han E
AD  - Department of Neurology, Affiliated Hospital of Shandong Medical University, 
      Jinan 250012.
FAU - Rajiv, J
AU  - Rajiv J
LA  - chi
PT  - Journal Article
PL  - China
TA  - Zhongguo Zhong Yao Za Zhi
JT  - Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese 
      materia medica
JID - 8913656
RN  - 0 (Amyloid beta-Protein Precursor)
RN  - 0 (Drugs, Chinese Herbal)
RN  - 0 (RNA, Messenger)
SB  - IM
MH  - Amyloid beta-Protein Precursor/*biosynthesis/genetics
MH  - Drugs, Chinese Herbal/*pharmacology
MH  - Gene Expression
MH  - Humans
MH  - Magnoliopsida
MH  - Neuroblastoma/pathology
MH  - *Plants, Medicinal
MH  - RNA, Messenger/*biosynthesis/genetics
MH  - Tumor Cells, Cultured/drug effects/metabolism
EDAT- 2001/10/16 10:00
MHDA- 2002/01/05 10:01
CRDT- 2001/10/16 10:00
PHST- 2001/10/16 10:00 [pubmed]
PHST- 2002/01/05 10:01 [medline]
PHST- 2001/10/16 10:00 [entrez]
PST - ppublish
SO  - Zhongguo Zhong Yao Za Zhi. 1998 Nov;23(11):691-3, inside back cover.