PMID- 11606688
OWN - NLM
STAT- MEDLINE
DCOM- 20011207
LR  - 20190501
IS  - 0022-3050 (Print)
IS  - 1468-330X (Electronic)
IS  - 0022-3050 (Linking)
VI  - 71
IP  - 5
DP  - 2001 Nov
TI  - Regression of ventral striatum hypometabolism after calcium/calcitriol therapy in 
      paroxysmal kinesigenic choreoathetosis due to idiopathic primary 
      hypoparathyroidism.
PG  - 691-5
AB  - A [(18)F]-FDG PET study was performed in a 44 year old man with proximal 
      kinesigenic choreoathetosis (PKC) secondary to idiopathic primary 
      hypoparathyroidism (IPH) before and 1 year after calcium/calcitriol therapy. The 
      [(18)F]-FDG PET performed before the start of the therapy disclosed a significant 
      bilateral hypometabolism in the ventral striatum. One year later, with the 
      patient still under calcium/calcitriol therapy and free of any occurrence of PKC 
      episodes, the [(18)F]-FDG PET did not show the previously detected 
      hypometabolism. The hypometabolism of the ventral striatum secondary to 
      hypocalcaemia seems to play a crucial part in the pathogenesis of paroxysmal 
      kinesigenic choreoathetosis associated with IPH.
FAU - Volonte, M A
AU  - Volonte MA
AD  - Movement Disorder Unit, Department of Neuroscience, Istituto Scientifico Ospedale 
      San Raffaele, Via Olgettina 60, 20132 Milano, Italy.
FAU - Perani, D
AU  - Perani D
FAU - Lanzi, R
AU  - Lanzi R
FAU - Poggi, A
AU  - Poggi A
FAU - Anchisi, D
AU  - Anchisi D
FAU - Balini, A
AU  - Balini A
FAU - Comi, G
AU  - Comi G
FAU - Fazio, F
AU  - Fazio F
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - England
TA  - J Neurol Neurosurg Psychiatry
JT  - Journal of neurology, neurosurgery, and psychiatry
JID - 2985191R
RN  - 0 (Radiopharmaceuticals)
RN  - 0Z5B2CJX4D (Fluorodeoxyglucose F18)
RN  - FXC9231JVH (Calcitriol)
RN  - IY9XDZ35W2 (Glucose)
RN  - SY7Q814VUP (Calcium)
SB  - IM
MH  - Adult
MH  - Basal Ganglia/diagnostic imaging/*metabolism/pathology
MH  - Brain Diseases, Metabolic/*chemically induced
MH  - Calcitriol/*adverse effects
MH  - Calcium/*adverse effects
MH  - Chorea/*drug therapy/*etiology
MH  - Fluorodeoxyglucose F18
MH  - Glucose/metabolism
MH  - Humans
MH  - Hypothyroidism/*complications
MH  - Magnetic Resonance Imaging
MH  - Male
MH  - Radiopharmaceuticals
MH  - Tomography, Emission-Computed
PMC - PMC1737590
EDAT- 2001/10/19 10:00
MHDA- 2002/01/05 10:01
PMCR- 2004/11/01
CRDT- 2001/10/19 10:00
PHST- 2001/10/19 10:00 [pubmed]
PHST- 2002/01/05 10:01 [medline]
PHST- 2001/10/19 10:00 [entrez]
PHST- 2004/11/01 00:00 [pmc-release]
AID - 10.1136/jnnp.71.5.691 [doi]
PST - ppublish
SO  - J Neurol Neurosurg Psychiatry. 2001 Nov;71(5):691-5. doi: 10.1136/jnnp.71.5.691.