PMID- 11669726
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20191120
IS  - 1520-510X (Electronic)
IS  - 0020-1669 (Linking)
VI  - 36
IP  - 7
DP  - 1997 Mar 26
TI  - Complex Formation and Ligand Substitution Reactions of 
      (2-Picolylamine)palladium(II) with Various Biologically Relevant Ligands. 
      Characterization of (2-Picolylamine)(1,1-cyclobutanedicarboxylato)palladium(II).
PG  - 1454-1463
AB  - The influence of a 2-picolylamine (pic) ligand on the reactivity of Pd(II) 
      complexes was investigated by detailed equilibrium and kinetic studies. Reactions 
      of [Pd(pic)(H(2)O)(2)](2+) with chloride, 1,1-cyclobutanedicarboxylic acid 
      (CBDCAH(2)), inosine (ino), and inosine 5'-monophosphate (5'-IMP) were studied. A 
      significantly higher reactivity for the first reaction step involving the 
      displacement of one coordinated solvent molecule on [Pd(pic)(H(2)O)(2)](2+) was 
      observed for the nucleoside inosine (k(10)( degrees )(C) = 25 400 +/- 200 M(-)(1) 
      s(-)(1)) than for the nucleotide 5'-IMP (k(10)( degrees )(C) = 7100 +/- 300 
      M(-)(1) s(-)(1)) and for CBDCAH(-) (k(25)( degrees )(C) = 5380 +/- 70 M(-)(1) 
      s(-)(1); DeltaH() = 54 +/- 2 kJ mol(-)(1); DeltaS() = 10 +/- 4 J K(-)(1) 
      mol(-)(1); DeltaV() = -0.2 +/- 0.7 cm(3) mol(-)(1)). The results are compared and 
      discussed in reference to data reported for closely related systems in the 
      literature. The molecular structure of [Pd(pic)(CBDCA)] in solution and in the 
      solid state was resolved. [Pd(pic)(CBDCA)].2H(2)O crystallizes in the space group 
      P2(1)/c (monoclinic, a = 5.659(5) A, b = 18.320(5) A, c = 14.027(5) A, beta = 
      97.748(5) degrees, V = 1440.94(14) A(3), Z = 4).
FAU - Rau, Tobias
AU  - Rau T
AD  - Institute for Inorganic Chemistry, University of Erlangen-Nurnberg, 
      Egerlandstrasse 1, 91058 Erlangen, Germany.
FAU - Shoukry, Mohamed
AU  - Shoukry M
FAU - van Eldik, Rudi
AU  - van Eldik R
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Inorg Chem
JT  - Inorganic chemistry
JID - 0366543
EDAT- 1997/03/26 00:00
MHDA- 2001/10/24 10:00
CRDT- 1997/03/26 00:00
PHST- 1997/03/26 00:00 [pubmed]
PHST- 2001/10/24 10:00 [medline]
PHST- 1997/03/26 00:00 [entrez]
AID - ic961192v [pii]
AID - 10.1021/ic961192v [doi]
PST - ppublish
SO  - Inorg Chem. 1997 Mar 26;36(7):1454-1463. doi: 10.1021/ic961192v.