PMID- 1167680
OWN - NLM
STAT- MEDLINE
DCOM- 19750510
LR  - 20190726
IS  - 0031-6768 (Print)
IS  - 0031-6768 (Linking)
VI  - 354
IP  - 3
DP  - 1975
TI  - M. Quadriceps femoris of man, a muscle with an unusual enzyme activity pattern of 
      energy supplying metabolism in mammals.
PG  - 249-55
AB  - 1. The following enzyme activities were estimated in needle-biopsy samples of the 
      lateral part of the human quadriceps femoris muscle: triosephosphate 
      dehydrogenase (TPDH), lactate dehydrogenase (LDH), NAD : glycerol-3-phosphate 
      dehydrogenase (GPDH), hexokinase (HK), NAD: malate dehydrogenase (MDH), citrate 
      synthase (CS) and hydroxyacyl-CoA dehydrogenase. 2. Although the enzyme 
      activities in muscles of women were lesser than in those of men, no difference 
      was found in the calculated enzyme activity ratios. There is thus no 
      sex-dependent metabolic type-differentiation in this muscle. 3. The human 
      quadriceps femoris is a low-activity muscle, in comparison with muscles of 
      homoiotherm laboratory animals. The enzyme activity ratio of TPDH to CS, 
      characterizing the glycolytic pyruvate formation to aerobic oxidative capacities, 
      shows this muscle to be of an intermediate type in this respect, similarly as the 
      extensor digitorum longus of the rat. The relatively very high capacity of 
      glucose phosphorylation (HK), the high aerobic regeneration of cytoplasmic 
      dehydrogenated NAD (GPDH) and the very low anaerobic regeneration (LDH), show the 
      unusually high proportion of carbohydrates (glucose) which can be broken down 
      aerobically.
FAU - Bass, A
AU  - Bass A
FAU - Vondra, K
AU  - Vondra K
FAU - Rath, R
AU  - Rath R
FAU - Vitek, V
AU  - Vitek V
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - Germany
TA  - Pflugers Arch
JT  - Pflugers Archiv : European journal of physiology
JID - 0154720
RN  - 72-89-9 (Acetyl Coenzyme A)
RN  - EC 1.1.- (Alcohol Oxidoreductases)
RN  - EC 1.1.- (Glycerolphosphate Dehydrogenase)
RN  - EC 1.1.1.27 (L-Lactate Dehydrogenase)
RN  - EC 1.1.1.37 (Malate Dehydrogenase)
RN  - EC 1.2.1.- (Glyceraldehyde-3-Phosphate Dehydrogenases)
RN  - EC 2.3.3.1 (Citrate (si)-Synthase)
RN  - EC 2.7.1.1 (Hexokinase)
SB  - IM
MH  - Acetyl Coenzyme A/metabolism
MH  - Alcohol Oxidoreductases/metabolism
MH  - Animals
MH  - Cheek
MH  - Citrate (si)-Synthase/metabolism
MH  - *Energy Metabolism
MH  - Female
MH  - Foot
MH  - Glyceraldehyde-3-Phosphate Dehydrogenases/metabolism
MH  - Glycerolphosphate Dehydrogenase/metabolism
MH  - Hexokinase/metabolism
MH  - Hindlimb
MH  - Humans
MH  - L-Lactate Dehydrogenase/metabolism
MH  - Leg
MH  - Malate Dehydrogenase/metabolism
MH  - Male
MH  - Muscles/*enzymology
MH  - Rabbits
MH  - Rats
MH  - Sex Factors
MH  - Species Specificity
MH  - *Thigh
EDAT- 1975/01/01 00:00
MHDA- 1975/01/01 00:01
CRDT- 1975/01/01 00:00
PHST- 1975/01/01 00:00 [pubmed]
PHST- 1975/01/01 00:01 [medline]
PHST- 1975/01/01 00:00 [entrez]
AID - 10.1007/BF00584648 [doi]
PST - ppublish
SO  - Pflugers Arch. 1975;354(3):249-55. doi: 10.1007/BF00584648.