PMID- 11682355
OWN - NLM
STAT- MEDLINE
DCOM- 20011212
LR  - 20190921
IS  - 1388-2457 (Print)
IS  - 1388-2457 (Linking)
VI  - 112
IP  - 11
DP  - 2001 Nov
TI  - Decreased sensory cortical excitability after 1 Hz rTMS over the ipsilateral 
      primary motor cortex.
PG  - 2154-8
AB  - OBJECTIVES: To study changes in the excitability of the sensory cortex by 
      repetitive transcranial magnetic stimulation (rTMS) in humans. METHODS: 
      Somatosensory evoked potentials (SEPs) and antidromic sensory nerve action 
      potentials (SNAPs) were elicited by right median nerve stimulation at the wrist 
      before and after low frequency (1 Hz) rTMS over the left motor cortex, lateral 
      premotor cortex, sensory cortex, and also after sham stimulation. The intensity 
      of rTMS was fixed at 1.1 times the active motor threshold at the hand area of 
      motor cortex. RESULTS: N20 peak (N20p)-P25 and P25-N33 amplitudes were suppressed 
      after rTMS over the motor cortex, whereas the N20 onset (N20o)-N20p and SNAP 
      amplitudes were not affected. They recovered to the baseline about 100 min after 
      the rTMS. rTMS over the premotor cortex or sensory cortex or sham stimulation had 
      no suppressive effect on SEPs. CONCLUSIONS: The reduction of N20p-P25 and P25-N33 
      components without any changes of N20o-N20p amplitude suggests that the 
      suppression occurs in the sensory cortex. rTMS (1 Hz) of the motor cortex induces 
      a long-lasting suppression of the ipsilateral sensory cortex even at an intensity 
      as low as 1.1 times the active motor threshold, probably via cortico-cortical 
      pathways between motor and sensory cortex.
FAU - Enomoto, H
AU  - Enomoto H
AD  - Department of Neurology, Division of Neuroscience, Graduate School of Medicine, 
      University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan.
FAU - Ugawa, Y
AU  - Ugawa Y
FAU - Hanajima, R
AU  - Hanajima R
FAU - Yuasa, K
AU  - Yuasa K
FAU - Mochizuki, H
AU  - Mochizuki H
FAU - Terao, Y
AU  - Terao Y
FAU - Shiio, Y
AU  - Shiio Y
FAU - Furubayashi, T
AU  - Furubayashi T
FAU - Iwata, N K
AU  - Iwata NK
FAU - Kanazawa, I
AU  - Kanazawa I
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Netherlands
TA  - Clin Neurophysiol
JT  - Clinical neurophysiology : official journal of the International Federation of 
      Clinical Neurophysiology
JID - 100883319
SB  - IM
MH  - Action Potentials/physiology
MH  - Adult
MH  - Differential Threshold
MH  - Electric Stimulation/methods
MH  - Evoked Potentials, Somatosensory/physiology
MH  - Female
MH  - Hand/physiology
MH  - Humans
MH  - Magnetics
MH  - Male
MH  - Median Nerve/physiology
MH  - Middle Aged
MH  - Motor Cortex/*physiology
MH  - Somatosensory Cortex/*physiology
MH  - Wrist/innervation
EDAT- 2001/10/30 10:00
MHDA- 2002/01/05 10:01
CRDT- 2001/10/30 10:00
PHST- 2001/10/30 10:00 [pubmed]
PHST- 2002/01/05 10:01 [medline]
PHST- 2001/10/30 10:00 [entrez]
AID - S1388-2457(01)00667-8 [pii]
AID - 10.1016/s1388-2457(01)00667-8 [doi]
PST - ppublish
SO  - Clin Neurophysiol. 2001 Nov;112(11):2154-8. doi: 10.1016/s1388-2457(01)00667-8.