PMID- 11696829
OWN - NLM
STAT- MEDLINE
DCOM- 20011218
LR  - 20191210
IS  - 0894-7317 (Print)
IS  - 0894-7317 (Linking)
VI  - 14
IP  - 11
DP  - 2001 Nov
TI  - Noncircumferential myofiber function: impact on early diastolic filling in 
      children.
PG  - 1065-9
AB  - Circumferential and noncircumferential myofiber contraction may have varying 
      impact on systolic and diastolic function. The purpose of this study was to 
      determine the relation of circumferential, longitudinal, and oblique fiber 
      shortening to early diastolic filling in children. Twenty-five patients (8.1 +/- 
      5.6 years of age; 12 boys and 13 girls) with normal echocardiograms and no heart 
      disease had prospective echocardiographic evaluation of circumferential 
      (shortening fraction, fractional area change), longitudinal (left ventricular 
      axial shortening), combined circumferential and longitudinal (left ventricular 
      ejection fraction), oblique (left ventricular systolic twist [LVST]) shortening, 
      and early diastolic filling. Mean LVST was 16 +/- 8 degrees. There was no 
      relation between early diastolic filling indexes and indexes of circumferential 
      or longitudinal shortening. However, there was a significant inverse relation 
      between heart rate-corrected E-wave acceleration time and LVST (r = 0.63, P 
      <.001). Oblique fiber shortening affects early diastolic filling in children. 
      Describing the functional role of noncircumferential left ventricular myofibers 
      may improve our understanding of global left ventricular function.
FAU - Michelfelder, E C
AU  - Michelfelder EC
AD  - Noninvasive Cardiac Imaging and Hemodynamic Research Laboratory, Division of 
      Cardiology, Children's Hospital Medical Center, 3333 Burnet Ave., OSB-4, 
      Cincinnati, OH 45229, USA. miche0@chmcc.org
FAU - Khoury, P
AU  - Khoury P
FAU - Witt, S A
AU  - Witt SA
FAU - Glascock, B J
AU  - Glascock BJ
FAU - Kimball, T R
AU  - Kimball TR
LA  - eng
PT  - Evaluation Study
PT  - Journal Article
PL  - United States
TA  - J Am Soc Echocardiogr
JT  - Journal of the American Society of Echocardiography : official publication of the 
      American Society of Echocardiography
JID - 8801388
SB  - IM
MH  - Adolescent
MH  - Child
MH  - Child, Preschool
MH  - Diastole
MH  - Echocardiography
MH  - Female
MH  - Heart Ventricles/diagnostic imaging
MH  - Humans
MH  - Infant
MH  - Infant, Newborn
MH  - Male
MH  - Muscle Fibers, Skeletal/*physiology
MH  - *Myocardial Contraction
MH  - Observer Variation
MH  - Regression Analysis
MH  - Reproducibility of Results
MH  - *Ventricular Function
EDAT- 2001/11/07 10:00
MHDA- 2002/01/05 10:01
CRDT- 2001/11/07 10:00
PHST- 2001/11/07 10:00 [pubmed]
PHST- 2002/01/05 10:01 [medline]
PHST- 2001/11/07 10:00 [entrez]
AID - S0894731701742824 [pii]
AID - 10.1067/mje.2001.114843 [doi]
PST - ppublish
SO  - J Am Soc Echocardiogr. 2001 Nov;14(11):1065-9. doi: 10.1067/mje.2001.114843.