PMID- 11699489
OWN - NLM
STAT- MEDLINE
DCOM- 20020116
LR  - 20131121
IS  - 0022-3492 (Print)
IS  - 0022-3492 (Linking)
VI  - 72
IP  - 10
DP  - 2001 Oct
TI  - Clinical comparison of microporous biocompatible composite of PMMA, PHEMA and 
      calcium hydroxide grafts and expanded polytetrafluoroethylene barrier membranes 
      in human mandibular molar Class II furcations. A case series.
PG  - 1451-9
AB  - BACKGROUND: Class II furcations present difficult treatment problems. Several 
      treatment approaches to obtain furcation fill have been used with varying 
      success. METHODS: The response of mandibular Class II furcations to treatment 
      with either a microporous biocompatible composite of PMMA 
      (poly-methyl-methacrylate), PHEMA (poly-hydroxyl-ethyl methacrylate) and calcium 
      hydroxide graft synthetic bone (HTR) replacement graft material; ePTFE barrier 
      membrane; or a combination of the two was evaluated in trios of mandibular molars 
      with Class II furcations in 8 patients with moderate to advanced periodontitis. 
      Following initial preparation, full-thickness flaps were raised in the areas 
      being treated, the bone and furcation defects debrided of granulomatous tissue, 
      and the involved root surfaces mechanically prepared and chemically conditioned. 
      By random allocation, HTR, ePTFE, or a combination of both was placed into and/or 
      fitted over the furcations, packed and/or secured in place, and the host flap 
      replaced or coronally positioned with sutures. Postsurgical deplaquing was 
      performed every 10 days leading up to ePTFE removal at approximately 6 weeks. 
      Continuing periodontal maintenance therapy was provided until surgical reentry at 
      6 months for documentation and any further necessary treatment. RESULTS: Direct 
      clinical measurements demonstrated essentially similar clinical results with all 
      3 treatments for bone and soft tissue changes. There were no statistically or 
      clinically significant differences except for better horizontal amount and 
      percent defect fill with HTR alone. Four of 8 furcations became Class I 
      clinically with HTR alone, 5 of 8 became Class I with ePTFE alone, and 5 of 8 
      with combination treatment. The only complete furcation closure occurred with 
      HTR. CONCLUSION: The findings of this study suggest essentially equal clinical 
      results with HTR bone replacement graft material alone, ePTFE barrier alone, and 
      a combination of the two in mandibular molar Class II furcations. However, a real 
      difference may not have been detected based on the small number of subjects in 
      the study.
FAU - Calongne, K B
AU  - Calongne KB
AD  - Periodontics Department, Baltimore College of Dental Surgery, University of 
      Maryland, Baltimore, MD, USA.
FAU - Aichelmann-Reidy, M E
AU  - Aichelmann-Reidy ME
FAU - Yukna, R A
AU  - Yukna RA
FAU - Mayer, E T
AU  - Mayer ET
LA  - eng
PT  - Clinical Trial
PT  - Comparative Study
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - J Periodontol
JT  - Journal of periodontology
JID - 8000345
RN  - 0 (Biocompatible Materials)
RN  - 0 (Bone Substitutes)
RN  - 0 (Membranes, Artificial)
RN  - 25249-16-5 (Polyhydroxyethyl Methacrylate)
RN  - 9002-84-0 (Polytetrafluoroethylene)
RN  - 9011-14-7 (Polymethyl Methacrylate)
RN  - PF5DZW74VN (Calcium Hydroxide)
SB  - IM
MH  - Biocompatible Materials/*therapeutic use
MH  - Bone Substitutes/*therapeutic use
MH  - Calcium Hydroxide/*therapeutic use
MH  - Debridement
MH  - Dental Plaque/prevention & control
MH  - Female
MH  - Furcation Defects/classification/*surgery
MH  - Gingival Recession/surgery
MH  - Granulation Tissue/surgery
MH  - Guided Tissue Regeneration, Periodontal/instrumentation/methods
MH  - Humans
MH  - Male
MH  - *Membranes, Artificial
MH  - Middle Aged
MH  - Molar/*surgery
MH  - Periodontal Attachment Loss/surgery
MH  - Periodontal Pocket/surgery
MH  - Periodontitis/surgery
MH  - Polyhydroxyethyl Methacrylate/*therapeutic use
MH  - Polymethyl Methacrylate/*therapeutic use
MH  - *Polytetrafluoroethylene
MH  - Porosity
MH  - Statistics as Topic
MH  - Statistics, Nonparametric
MH  - Surgical Flaps
MH  - Tooth Root/surgery
MH  - Wound Healing
EDAT- 2001/11/09 10:00
MHDA- 2002/01/17 10:01
CRDT- 2001/11/09 10:00
PHST- 2001/11/09 10:00 [pubmed]
PHST- 2002/01/17 10:01 [medline]
PHST- 2001/11/09 10:00 [entrez]
AID - 10.1902/jop.2001.72.10.1451 [doi]
PST - ppublish
SO  - J Periodontol. 2001 Oct;72(10):1451-9. doi: 10.1902/jop.2001.72.10.1451.