PMID- 11714419
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200929
IS  - 1468-6708 (Print)
IS  - 1468-6694 (Electronic)
IS  - 1468-6694 (Linking)
VI  - 1
IP  - 2
DP  - 2000
TI  - Debate: Do all patients with heart failure require automatic implantable 
      defibrillators for the prevention of sudden death?
PG  - 95-97
AB  - Recent clinical trials indicate that approximately two-thirds of patients in New 
      York Heart Association (NYHA) class II and III, who comprise almost 90% of 
      patients with heart failure, die suddenly. Patients in NYHA class IV usually die 
      of progressive heart failure. Implantation of implantable cardioverters 
      defibrillators (ICDs) in this population would represent a huge logistic problem 
      and economic expense. Clinical trials have recently demonstrated that 
      beta-blocker therapy with carvedilol, bisoprolol, and toprol XL decrease the 
      sudden death rate by almost 50%, in addition to impacting significantly on death 
      due to worsening heart failure. This medical approach is beneficial to all 
      patients, and should be our major therapy. However, it is reasonable to attempt 
      to identify that subpopulations of heart failure patients who could benefit from 
      an ICD.
FAU - Goldstein, Sidney
AU  - Goldstein S
AD  - Henry Ford Hospital, Detroit, Michigan, and Case-Western Reserve University, 
      Cleveland, Ohio, USA. sgoldst1@hfhs.org
LA  - eng
PT  - Journal Article
PL  - England
TA  - Curr Control Trials Cardiovasc Med
JT  - Current controlled trials in cardiovascular medicine
JID - 100968052
PMC - PMC59608
EDAT- 2001/11/21 10:00
MHDA- 2001/11/21 10:01
PMCR- 2000/10/11
CRDT- 2001/11/21 10:00
PHST- 2000/05/01 00:00 [received]
PHST- 2000/09/05 00:00 [revised]
PHST- 2000/09/11 00:00 [accepted]
PHST- 2001/11/21 10:00 [pubmed]
PHST- 2001/11/21 10:01 [medline]
PHST- 2001/11/21 10:00 [entrez]
PHST- 2000/10/11 00:00 [pmc-release]
AID - cvm-1-2-095 [pii]
AID - 10.1186/cvm-1-2-095 [doi]
PST - ppublish
SO  - Curr Control Trials Cardiovasc Med. 2000;1(2):95-97. doi: 10.1186/cvm-1-2-095.