PMID- 11717581 OWN - NLM STAT- MEDLINE DCOM- 20020124 LR - 20071114 IS - 0968-0519 (Print) IS - 0968-0519 (Linking) VI - 7 IP - 4 DP - 2001 TI - Identification of Toll-like receptor 4 (Tlr4) as the sole conduit for LPS signal transduction: genetic and evolutionary studies. PG - 277-80 FAU - Beutler, B AU - Beutler B AD - Department of Immunology, The Scripps Research Institute, La Jolla, California 92037, USA. bruce@scripps.edu FAU - Du, X AU - Du X FAU - Poltorak, A AU - Poltorak A LA - eng GR - 1R01-GM60031-03/GM/NIGMS NIH HHS/United States PT - Journal Article PT - Research Support, U.S. Gov't, P.H.S. PT - Review PL - United States TA - J Endotoxin Res JT - Journal of endotoxin research JID - 9433350 RN - 0 (Drosophila Proteins) RN - 0 (Lipopolysaccharides) RN - 0 (Membrane Glycoproteins) RN - 0 (Receptors, Cell Surface) RN - 0 (TLR4 protein, human) RN - 0 (Toll-Like Receptor 4) RN - 0 (Toll-Like Receptors) SB - IM MH - Animals MH - *Drosophila Proteins MH - *Evolution, Molecular MH - Humans MH - Lipopolysaccharides/*pharmacology MH - Membrane Glycoproteins/genetics/metabolism/*physiology MH - Receptors, Cell Surface/genetics/metabolism/*physiology MH - Signal Transduction/*genetics MH - Toll-Like Receptor 4 MH - Toll-Like Receptors RF - 33 EDAT- 2001/11/22 10:00 MHDA- 2002/01/25 10:01 CRDT- 2001/11/22 10:00 PHST- 2001/11/22 10:00 [pubmed] PHST- 2002/01/25 10:01 [medline] PHST- 2001/11/22 10:00 [entrez] PST - ppublish SO - J Endotoxin Res. 2001;7(4):277-80.