PMID- 11735038 OWN - NLM STAT- MEDLINE DCOM- 20020206 LR - 20131121 IS - 0302-766X (Print) IS - 0302-766X (Linking) VI - 306 IP - 3 DP - 2001 Dec TI - Sexually dimorphic neurogenesis is topographically matched with the anterior accessory olfactory bulb of the adult rat. PG - 385-9 AB - The accessory olfactory bulb (AOB) is a sexually dimorphic structure of the vomeronasal system, which plays a role in the control of sexual behaviors. In adult rats, we have demonstrated previously that the migrating neuroblasts of the subependymal layer (SEL) directed to the main olfactory bulb (MOB) also reach the AOB. To tackle the relation between sexual dimorphism and targeted cell migration, we quantified the neo-neurogenesis in the AOB of adult rats of both sexes. Our results confirm a morphological sexual dimorphism in the AOB granular layer volumes. We showed that the number of newly generated cells reaching the AOB in both sexes was considerable, even if lower than those directed to the MOB. Moreover, we demonstrated that the rate of neurogenesis in the anterior AOB of the two sexes was significantly different. FAU - Peretto, P AU - Peretto P AD - Department of Animal and Human Biology, University of Turin, via Accademia Albertina 13, 10123 Turin, Italy. FAU - Giachino, C AU - Giachino C FAU - Panzica, G C AU - Panzica GC FAU - Fasolo, A AU - Fasolo A LA - eng PT - Comparative Study PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20011010 PL - Germany TA - Cell Tissue Res JT - Cell and tissue research JID - 0417625 RN - 0 (Antimetabolites) RN - G34N38R2N1 (Bromodeoxyuridine) SB - IM MH - Age Factors MH - Animals MH - Antimetabolites/analysis/pharmacology MH - Bromodeoxyuridine/analysis/pharmacology MH - Cell Count MH - Cell Division/physiology MH - Cell Movement/physiology MH - Cell Nucleus/chemistry MH - Ependyma/cytology MH - Female MH - Immunohistochemistry MH - Male MH - Neurons/chemistry/*cytology MH - Olfactory Bulb/*cytology MH - Rats MH - Rats, Wistar MH - *Sex Characteristics EDAT- 2001/12/06 10:00 MHDA- 2002/02/07 10:01 CRDT- 2001/12/06 10:00 PHST- 2001/04/27 00:00 [received] PHST- 2001/08/28 00:00 [accepted] PHST- 2001/12/06 10:00 [pubmed] PHST- 2002/02/07 10:01 [medline] PHST- 2001/12/06 10:00 [entrez] AID - 10.1007/s00441-001-0471-1 [doi] PST - ppublish SO - Cell Tissue Res. 2001 Dec;306(3):385-9. doi: 10.1007/s00441-001-0471-1. Epub 2001 Oct 10.