PMID- 11737252
OWN - NLM
STAT- MEDLINE
DCOM- 20011218
LR  - 20190910
IS  - 0902-4441 (Print)
IS  - 0902-4441 (Linking)
VI  - 67
IP  - 3
DP  - 2001 Sep
TI  - Hairy cell leukemia in first cousins and review of the literature.
PG  - 185-8
AB  - Familial hairy cell leukemia (HCL) occurs rarely. So far, 26 familial instances 
      of HCL (in 12 families) have been reported in the literature. The consistent 
      human leukocyte antigen (HLA) linkage could not be established in most cases of 
      familial HCL. History of exposure to organic chemicals or employment in 
      woodworking or farming was noted in only two out of 11 affected families. We 
      present two familial cases of HCL as well as a thorough literature review. An 
      influence of HLA or farming themselves on a predisposition to HCL remains 
      unproven but does not rule out an HLA-linked and as yet unidentified gene 
      responsible for increased disease susceptibility. HCL in families is unlikely to 
      be due to random patterning, but there are insufficient data so far to decisively 
      incriminate either HLA-related or environmental causative factors.
FAU - Colovic, M D
AU  - Colovic MD
AD  - Institute of Hematology, University Clinical Center, Belgrade, Serbia, 
      Yugoslavia. marcolov@EUnet.yu
FAU - Jankovic, G M
AU  - Jankovic GM
FAU - Wiernik, P H
AU  - Wiernik PH
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - England
TA  - Eur J Haematol
JT  - European journal of haematology
JID - 8703985
RN  - 0 (HLA Antigens)
SB  - IM
MH  - Genetic Linkage
MH  - Genetic Predisposition to Disease
MH  - HLA Antigens/*genetics
MH  - Humans
MH  - Leukemia, Hairy Cell/*genetics/pathology
MH  - Male
MH  - Middle Aged
EDAT- 2001/12/12 10:00
MHDA- 2002/01/05 10:01
CRDT- 2001/12/12 10:00
PHST- 2001/12/12 10:00 [pubmed]
PHST- 2002/01/05 10:01 [medline]
PHST- 2001/12/12 10:00 [entrez]
AID - 478 [pii]
AID - 10.1034/j.1600-0609.2001.5790478.x [doi]
PST - ppublish
SO  - Eur J Haematol. 2001 Sep;67(3):185-8. doi: 10.1034/j.1600-0609.2001.5790478.x.