PMID- 11737746 OWN - NLM STAT- MEDLINE DCOM- 20020212 LR - 20191105 IS - 1328-8067 (Print) IS - 1328-8067 (Linking) VI - 43 IP - 6 DP - 2001 Dec TI - Postoperative speech development based on cleft types in children with cleft palate. PG - 666-72 AB - BACKGROUND: The purpose of this historical cohort study was to compare the speech development of children with three types of cleft palate while controlling for some confounding factors. METHODS: Subjects included 28 children with bilateral cleft lip and palate (BCLP), 74 with unilateral cleft lip and palate (UCLP), 33 with isolated cleft palate (ICP), and 168 normal control children. Children with cleft palate attended a speech clinic in Fukuoka, had attained adequate velopharyngeal function after palatoplasty carried out within 18 months after birth, and had no syndromic diseases, persistent hearing loss, mental retardation, or central nervous system problems. RESULTS: Children with BCLP began using two-word sentences later than other children (3 months, P<0.01). However, the difference based on sex was also statistically significant. Female patients started using two-word sentences earlier than male patients (2 months, P<0.01). Children with BCLP had lower verbal scores on the Wechsler Preschool and Primary Scale of Intelligence (WPPSI) than other children (12.4-14.9 points, P<0.01). There was no significant difference based on sex. CONCLUSIONS: The results of this research indicate the following: speech development of children with ICP and UCLP was similar to that of normal children; however, speech development of children with BCLP was delayed compared with other children with or without cleft palate. FAU - Nakajima, T AU - Nakajima T AD - Speech Clinic, St. Mary's Hospital, 422 Tsubukuhonmachi, Kurumeshi, Fukuoka 830-8543, Japan. nakajima2467@st-mary-med.or.jp FAU - Mitsudome, A AU - Mitsudome A FAU - Yosikawa, A AU - Yosikawa A LA - eng PT - Comparative Study PT - Journal Article PL - Australia TA - Pediatr Int JT - Pediatrics international : official journal of the Japan Pediatric Society JID - 100886002 SB - IM MH - Age Factors MH - Child, Preschool MH - Cleft Lip/complications/*surgery MH - Cleft Palate/complications/*surgery MH - Cohort Studies MH - Female MH - Humans MH - Infant MH - Intelligence MH - Language Development Disorders/*etiology MH - Male MH - Postoperative Care MH - Sex Factors MH - *Speech Intelligibility MH - Wechsler Scales EDAT- 2001/12/12 10:00 MHDA- 2002/02/13 10:01 CRDT- 2001/12/12 10:00 PHST- 2001/12/12 10:00 [pubmed] PHST- 2002/02/13 10:01 [medline] PHST- 2001/12/12 10:00 [entrez] AID - 1478 [pii] AID - 10.1046/j.1442-200x.2001.01478.x [doi] PST - ppublish SO - Pediatr Int. 2001 Dec;43(6):666-72. doi: 10.1046/j.1442-200x.2001.01478.x.