PMID- 11763093
OWN - NLM
STAT- MEDLINE
DCOM- 20020123
LR  - 20191210
IS  - 0003-2654 (Print)
IS  - 0003-2654 (Linking)
VI  - 126
IP  - 11
DP  - 2001 Nov
TI  - Application of SERS spectroscopy to the identification of 
      (3,4-methylenedioxy)amphetamine in forensic samples utilizing matrix stabilized 
      silver halides.
PG  - 2066-71
AB  - A method based on surface-enhanced Raman scattering (SERS) spectroscopy was 
      developed to meet the need for the reliable and rapid identification of illicit 
      drugs such as the 'designer drug' XTC, preferably to increase the security of 
      legal certificates. A matrix stabilized silver halide dispersion on a microtiter 
      plate is used as the SERS-active substrate, providing an easy to use system for 
      sample preparation and probing by means of a Raman microscope. The potential of 
      the method is demonstrated by applying it to the identification of the 
      psychoactive ingredients of drug containing tablets which were confiscated by the 
      local police at techno-music events. The samples of interest were 26 different 
      brands of XTC tablets and several pieces of evidence (powders) containing 
      amphetamine. For reference, we show SERS and Raman spectra of pristine 
      amphetamine, methamphetamine, 3,4-methylenedioxyamphetamine, 
      3,4-methylenedioxymethamphetamine (MDMA) and 3,4-methylenedioxyethamphetamine.
FAU - Sagmuller, B
AU  - Sagmuller B
AD  - Institiut fur Physikalische und Theoretische Chemie, 
      Friedrich-Alexander-Universitat Erlangen-Nurnberg, Germany.
FAU - Schwarze, B
AU  - Schwarze B
FAU - Brehm, G
AU  - Brehm G
FAU - Schneider, S
AU  - Schneider S
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Analyst
JT  - The Analyst
JID - 0372652
RN  - 0 (Illicit Drugs)
RN  - 44RAL3456C (Methamphetamine)
RN  - 4764-17-4 (3,4-Methylenedioxyamphetamine)
RN  - CK833KGX7E (Amphetamine)
RN  - KE1SEN21RM (N-Methyl-3,4-methylenedioxyamphetamine)
RN  - ML1I4KK67B (3,4-methylenedioxyethamphetamine)
SB  - IM
MH  - 3,4-Methylenedioxyamphetamine/*analogs & derivatives/*analysis
MH  - Amphetamine/analysis
MH  - Illicit Drugs/*chemistry
MH  - Methamphetamine/analysis
MH  - N-Methyl-3,4-methylenedioxyamphetamine/analysis
MH  - Spectrum Analysis, Raman
EDAT- 2002/01/05 10:00
MHDA- 2002/01/24 10:01
CRDT- 2002/01/05 10:00
PHST- 2002/01/05 10:00 [pubmed]
PHST- 2002/01/24 10:01 [medline]
PHST- 2002/01/05 10:00 [entrez]
AID - 10.1039/b105321n [doi]
PST - ppublish
SO  - Analyst. 2001 Nov;126(11):2066-71. doi: 10.1039/b105321n.