PMID- 11764184
OWN - NLM
STAT- MEDLINE
DCOM- 20020607
LR  - 20071115
IS  - 1090-3798 (Print)
IS  - 1090-3798 (Linking)
VI  - 5
IP  - 6
DP  - 2001
TI  - Lack of association between childhood stroke after varicella and human leukocyte 
      antigen (HLA)-B51.
PG  - 259-60
AB  - Human leukocyte antigen (HLA)-B51 has been suggested as an immunogenetic marker 
      for a genetic predisposition to vascular occlusion in response to an 
      immunological stimulus. Varicella has been reported to be a possible risk factor 
      for stroke. We performed DNA-based HLA typing in 11 young patients (mean age: 5.2 
      years) with unexplained ischaemic stroke. In eight of them varicella had occurred 
      before their stroke. HLA-B51 was negative in all 11 patients and we did not find 
      any significant accumulation of other HLA-subgroups. Our study does not support 
      an association between susceptibility to stroke after varicella and HLA-B51.
FAU - Kluger, G
AU  - Kluger G
AD  - Neuropediatric Department, BHZ Vogtareuth, Germany. g.kluger@bhz-vogtareuth.de
FAU - Hubmann, M
AU  - Hubmann M
FAU - Vogler, L
AU  - Vogler L
FAU - Berz, K
AU  - Berz K
LA  - eng
PT  - Journal Article
PL  - England
TA  - Eur J Paediatr Neurol
JT  - European journal of paediatric neurology : EJPN : official journal of the 
      European Paediatric Neurology Society
JID - 9715169
RN  - 0 (HLA Antigens)
RN  - 0 (Protein C)
RN  - 0 (Protein S)
SB  - IM
MH  - Chickenpox/*immunology
MH  - Child
MH  - Child, Preschool
MH  - Female
MH  - HLA Antigens/*immunology
MH  - Humans
MH  - Male
MH  - Protein C/metabolism
MH  - Protein S/metabolism
MH  - Retrospective Studies
MH  - Stroke/*immunology/metabolism
EDAT- 2002/01/05 10:00
MHDA- 2002/06/12 10:01
CRDT- 2002/01/05 10:00
PHST- 2002/01/05 10:00 [pubmed]
PHST- 2002/06/12 10:01 [medline]
PHST- 2002/01/05 10:00 [entrez]
AID - S1090-3798(01)90526-4 [pii]
AID - 10.1053/ejpn.2001.0526 [doi]
PST - ppublish
SO  - Eur J Paediatr Neurol. 2001;5(6):259-60. doi: 10.1053/ejpn.2001.0526.