PMID- 11775702
OWN - NLM
STAT- MEDLINE
DCOM- 20020531
LR  - 20161230
IS  - 1566-0702 (Print)
IS  - 1566-0702 (Linking)
VI  - 94
IP  - 1-2
DP  - 2001 Dec 10
TI  - Brain-derived neurotrophic factor and vanilloid receptor subtype 1 immunoreactive 
      sensory DRG neurons innervating the lumbar facet joints in rats.
PG  - 132-5
AB  - The rat L5/6 facet joint is innervated from L1 to L6 by the dorsal root ganglia 
      (DRG). The presence of substance P- and calcitonin gene-related 
      peptide-immunoreactive (ir) DRG neurons innervating the L5/6 facet joint has been 
      demonstrated. However, the presence of brain-derived neurotrophic factor 
      (BDNF)-ir and the vanilloid receptor subtype 1 (VR1)-ir DRG neurons, which relate 
      to inflammatory and burning pain innervating the L5/6 facet joint, has not. 
      Fluoro-gold (FG)-labeled neurons innervating the L5/6 facet joint were 
      distributed throughout the DRGs from T13 to L6 levels. Of the FG-labeled neurons, 
      the proportions of BDNF-ir in L1, L2, L3, L4 and L5 DRG neurons were 9%, 15%, 
      21%, 17% and 20% and the proportions of VR1-ir L1, L2, L3, L4 and L5 DRG neurons 
      were 8%, 9%, 15%, 16% and 15%, respectively.
FAU - Ohtori, S
AU  - Ohtori S
AD  - Department of Orthopaedic Surgery, School of Medicine, Chiba University, Japan. 
      s.c.oh@pref-hosp.togane.chiba.jp
FAU - Takahashi, K
AU  - Takahashi K
FAU - Chiba, T
AU  - Chiba T
FAU - Yamagata, M
AU  - Yamagata M
FAU - Sameda, H
AU  - Sameda H
FAU - Moriya, H
AU  - Moriya H
LA  - eng
PT  - Journal Article
PL  - Netherlands
TA  - Auton Neurosci
JT  - Autonomic neuroscience : basic & clinical
JID - 100909359
RN  - 0 (Brain-Derived Neurotrophic Factor)
RN  - 0 (Receptors, Drug)
RN  - 0 (TRPV Cation Channels)
RN  - 0 (TRPV1 receptor)
SB  - IM
MH  - Animals
MH  - Brain-Derived Neurotrophic Factor/*metabolism
MH  - Ganglia, Spinal/cytology/*metabolism
MH  - Immunohistochemistry
MH  - Joints/*innervation
MH  - Lumbar Vertebrae/*innervation
MH  - Male
MH  - Microscopy, Fluorescence
MH  - Neurons, Afferent/*metabolism
MH  - Nociceptors/physiology
MH  - Rats
MH  - Rats, Sprague-Dawley
MH  - Receptors, Drug/*metabolism
MH  - TRPV Cation Channels
MH  - Tissue Fixation
EDAT- 2002/01/05 10:00
MHDA- 2002/06/01 10:01
CRDT- 2002/01/05 10:00
PHST- 2002/01/05 10:00 [pubmed]
PHST- 2002/06/01 10:01 [medline]
PHST- 2002/01/05 10:00 [entrez]
AID - S1566-0702(01)00343-5 [pii]
AID - 10.1016/S1566-0702(01)00343-5 [doi]
PST - ppublish
SO  - Auton Neurosci. 2001 Dec 10;94(1-2):132-5. doi: 10.1016/S1566-0702(01)00343-5.