PMID- 11776908 OWN - NLM STAT- MEDLINE DCOM- 20020312 LR - 20171116 IS - 1002-0098 (Print) IS - 1002-0098 (Linking) VI - 34 IP - 4 DP - 1999 Jul TI - [Infiltration of monocytes/macrophages and expression of monocyte chemoattractant protein-1 in gingival tissues from patients with rapidly progressive periodontitis]. PG - 214-6 AB - OBJECTIVE: To find if there was any difference in monocytes/macrophages infiltration and monocyte chemoattractant protein-1(MCP-1) expression between rapidly progressive periodontitis (RPP) and adult periodontitis (AP) tissues. METHODS: Inflamed gingival specimens (20) were obtained from RPP(14) and AP(6) patients, and specimens from clinically healthy subjects (H,6) as control. The monocytes/macrophages and MCP-1 expression were detected by immuno-histochemistry SP assay with antibodies against CD14 and CD68, and rabbit anti-MCP-1 antibody. RESULTS: There were no differences in the mean counts (+/- SD) of monocytes/macrophages and MCP-1 positive cells between RPP and AP groups. CONCLUSION: Though rapid and severe periodontal destruction occurs in RPP, there is no differences in monocytes/macrophages infiltration and MCP-1 expression in gingival tissues between rapidly progressive periodontitis and adult periodontitis patients. FAU - Zhu, X AU - Zhu X AD - School of Stomatology, Beijing Medical University, Beijing 100081. FAU - Meng, H AU - Meng H FAU - Chen, Z AU - Chen Z LA - chi PT - Journal Article PL - China TA - Zhonghua Kou Qiang Yi Xue Za Zhi JT - Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology JID - 8711066 RN - 0 (Antigens, CD) RN - 0 (Antigens, Differentiation, Myelomonocytic) RN - 0 (CD68 antigen, human) RN - 0 (Chemokine CCL2) RN - 0 (Lipopolysaccharide Receptors) SB - IM MH - Adult MH - Antigens, CD/analysis MH - Antigens, Differentiation, Myelomonocytic/analysis MH - Chemokine CCL2/*biosynthesis MH - Gingivitis/*metabolism/pathology MH - Humans MH - Immunohistochemistry MH - Lipopolysaccharide Receptors/analysis MH - Macrophages/*metabolism/pathology MH - Monocytes/*metabolism/pathology MH - Periodontitis/*metabolism/pathology EDAT- 2002/01/05 10:00 MHDA- 2002/03/13 10:01 CRDT- 2002/01/05 10:00 PHST- 2002/01/05 10:00 [pubmed] PHST- 2002/03/13 10:01 [medline] PHST- 2002/01/05 10:00 [entrez] PST - ppublish SO - Zhonghua Kou Qiang Yi Xue Za Zhi. 1999 Jul;34(4):214-6.