PMID- 11786721 OWN - NLM STAT- MEDLINE DCOM- 20020206 LR - 20180213 IS - 0025-7931 (Print) IS - 0025-7931 (Linking) VI - 68 IP - 6 DP - 2001 TI - Concurrent left-sided spontaneous pneumothorax in Japanese monogerminal twins. PG - 625-7 AB - Monogerminal twin brothers aged 17 were admitted because of concurrent left-sided spontaneous pneumothorax. A familial background of this common disease in association with the human leukocyte antigen (HLA) has been suggested; however, the actual mode of inheritance in association with HLA typing is still uncertain. HLA analysis in this family revealed the HLA-A24, B61 (40), Cw3, DR4, DR53, and DQ3 haplotype in the twins and their father, who also had a medical history of spontaneous pneumothorax. We report these cases as an extremely rare example of familial occurrence of spontaneous pneumothorax. CI - Copyright 2001 S. Karger AG, Basel FAU - Tsukadaira, A AU - Tsukadaira A AD - First Department of Internal Medicine, Shinshu University School of Medicine, Matsumoto, Japan. FAU - Okubo, Y AU - Okubo Y FAU - Ota, M AU - Ota M FAU - Hotta, J AU - Hotta J FAU - Kubo, K AU - Kubo K LA - eng PT - Journal Article PL - Switzerland TA - Respiration JT - Respiration; international review of thoracic diseases JID - 0137356 RN - 0 (HLA Antigens) SB - IM MH - Adolescent MH - Diseases in Twins/*genetics MH - HLA Antigens/*analysis MH - Haplotypes MH - Humans MH - Male MH - Pneumothorax/*genetics/immunology MH - Twins, Monozygotic EDAT- 2002/01/12 10:00 MHDA- 2002/02/07 10:01 CRDT- 2002/01/12 10:00 PHST- 2002/01/12 10:00 [pubmed] PHST- 2002/02/07 10:01 [medline] PHST- 2002/01/12 10:00 [entrez] AID - res68625 [pii] AID - 10.1159/000050585 [doi] PST - ppublish SO - Respiration. 2001;68(6):625-7. doi: 10.1159/000050585.