PMID- 11792478
OWN - NLM
STAT- MEDLINE
DCOM- 20020313
LR  - 20190916
IS  - 0303-8467 (Print)
IS  - 0303-8467 (Linking)
VI  - 104
IP  - 1
DP  - 2002 Jan
TI  - Successful treatment of ventriculostomy-related meningitis caused by 
      vancomycin-resistant Enterococcus with intravenous and intraventricular 
      quinupristin/dalfopristin.
PG  - 54-6
AB  - We report a case of ventriculostomy-related meningitis caused by 
      vancomycin-resistant Enterococcus faecium (VRE). The patient was successfully 
      treated with administration of quinupristin/dalfopristin by both intravenous and 
      intraventricular routes. A brief review of the literature is provided, which 
      indicates that optimal management with quinupristin/dalfopristin should include 
      daily intraventricular doses of at least 2 mg.
FAU - Williamson, John C
AU  - Williamson JC
AD  - Department of Pharmacy, Wake Forest University Baptist Medical Center, Medical 
      Center Boulevard, Winston-Salem, NC 27157, USA. johnwill@wfubmc.edu
FAU - Glazier, Steven S
AU  - Glazier SS
FAU - Peacock, James E Jr
AU  - Peacock JE Jr
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - Netherlands
TA  - Clin Neurol Neurosurg
JT  - Clinical neurology and neurosurgery
JID - 7502039
RN  - 11006-76-1 (Virginiamycin)
RN  - 126602-89-9 (quinupristin-dalfopristin)
SB  - IM
MH  - Drug Therapy, Combination/administration & dosage/*therapeutic use
MH  - Enterococcus/drug effects/*pathogenicity
MH  - Female
MH  - Humans
MH  - Infusions, Intravenous
MH  - Injections, Intraventricular
MH  - Meningitis, Bacterial/*drug therapy/etiology
MH  - Middle Aged
MH  - Treatment Outcome
MH  - *Vancomycin Resistance
MH  - Ventriculostomy/*adverse effects
MH  - Virginiamycin/administration & dosage/*therapeutic use
EDAT- 2002/01/17 10:00
MHDA- 2002/03/14 10:01
CRDT- 2002/01/17 10:00
PHST- 2002/01/17 10:00 [pubmed]
PHST- 2002/03/14 10:01 [medline]
PHST- 2002/01/17 10:00 [entrez]
AID - S0303846701001809 [pii]
AID - 10.1016/s0303-8467(01)00180-9 [doi]
PST - ppublish
SO  - Clin Neurol Neurosurg. 2002 Jan;104(1):54-6. doi: 10.1016/s0303-8467(01)00180-9.