PMID- 11793673
OWN - NLM
STAT- MEDLINE
DCOM- 20020415
LR  - 20191105
IS  - 0741-0395 (Print)
IS  - 0741-0395 (Linking)
VI  - 21 Suppl 1
DP  - 2001
TI  - Quantitative trait loci mapping of serum IgE in an isolated Hutterite population.
PG  - S224-9
AB  - Serum immunoglobulin E (IgE) is a quantitative trait associated with asthma. A 
      variance components approach to the analysis of data from a subset of a founder 
      population of Hutterites indicated that over half the variability in IgE levels 
      may be due to genes. Two variance components methods suggest that the genetic 
      model underlying IgE does not consist of a single major gene, but of multiple 
      loci with more modest effects. Both approaches identified putative quantitative 
      trait loci on chromosomes 1 and 21.
FAU - Alarcon, M
AU  - Alarcon M
AD  - Department of Neurology, Center for Neurobehavioral Genetics and Neuropsychiatric 
      Research Institute, Los Angeles, California, USA.
FAU - Cantor, R M
AU  - Cantor RM
LA  - eng
GR  - HL-28481/HL/NHLBI NIH HHS/United States
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - United States
TA  - Genet Epidemiol
JT  - Genetic epidemiology
JID - 8411723
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Adult
MH  - Analysis of Variance
MH  - Asthma/epidemiology/*genetics
MH  - Child
MH  - Chromosome Mapping/*statistics & numerical data
MH  - Chromosomes, Human, Pair 1
MH  - Chromosomes, Human, Pair 21
MH  - *Consanguinity
MH  - Female
MH  - Gene Frequency
MH  - Genetics, Population
MH  - Humans
MH  - Immunoglobulin E/*blood
MH  - Male
MH  - *Quantitative Trait, Heritable
MH  - South Dakota
EDAT- 2002/01/17 10:00
MHDA- 2002/04/16 10:01
CRDT- 2002/01/17 10:00
PHST- 2002/01/17 10:00 [pubmed]
PHST- 2002/04/16 10:01 [medline]
PHST- 2002/01/17 10:00 [entrez]
AID - 10.1002/gepi.2001.21.s1.s224 [doi]
PST - ppublish
SO  - Genet Epidemiol. 2001;21 Suppl 1:S224-9. doi: 10.1002/gepi.2001.21.s1.s224.