PMID- 11805962
OWN - NLM
STAT- MEDLINE
DCOM- 20020305
LR  - 20061115
IS  - 1043-0679 (Print)
IS  - 1043-0679 (Linking)
VI  - 13
IP  - 4 Suppl 1
DP  - 2001 Oct
TI  - Comparison of late outcome after stentless versus stented xenograft aortic valve 
      replacement.
PG  - 136-42
AB  - The long-term outcomes of 292 patients having stented xenograft aortic valve 
      replacement (AVR) (group 1) and 376 having stentless AVR (group 2) were compared. 
      Patients in group 1 were older (75 +/- 9 years v 70 +/- 6 years, P =.01), had 
      more advanced cardiac disease (New York Heart Association [NYHA] classification 
      III-IV: 85% v 75%, P =.03), and more associated procedures (53% v 41%, P =.01). 
      Early mortality was higher in Group 1 (6.2% v 2.6%, P =.02), primarily due to 
      cardiac cause (5.4% v 1.5%, P =.009). During follow-up (37 +/- 30 months v 43 +/- 
      35 months, P = not significant [ns]), 66 late deaths were recorded (12% v 9%, P = 
      ns). At 8 years, survival (70% +/- 5% v 81% +/- 3%, P =.01) freedom from cardiac 
      death (85% +/- 1% v 92% +/- 3%, P =.02) and prosthesis-related death (79% +/- 5% 
      v 95% +/- 2%, P =.004) was higher in Group 2, but freedom from structural 
      deterioration was similar (92% +/- 5% v 93% +/- 3%, P = ns). Late functional 
      status was equally satisfactory (NYHA classification I-II: 89% v 90%, P = ns). 
      Stentless AVR may confer selective survival advantages. Because freedom from 
      valve failure is similar to stented xenografts, extension of stentless AVR to 
      patients without anatomic contraindications appears justified.
CI  - Copyright 2001 by W.B. Saunders Company
FAU - Luciani, G B
AU  - Luciani GB
AD  - Division of Cardiac Surgery, University of Verona, Verona, Italy.
FAU - Auriemma, S
AU  - Auriemma S
FAU - Santini, F
AU  - Santini F
FAU - Casali, G
AU  - Casali G
FAU - Barozzi, L
AU  - Barozzi L
FAU - Mazzucco, A
AU  - Mazzucco A
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - United States
TA  - Semin Thorac Cardiovasc Surg
JT  - Seminars in thoracic and cardiovascular surgery
JID - 8917640
SB  - IM
MH  - Actuarial Analysis
MH  - Aged
MH  - Aged, 80 and over
MH  - Aortic Valve/*surgery
MH  - *Bioprosthesis
MH  - Female
MH  - Follow-Up Studies
MH  - Heart Valve Prosthesis/*adverse effects
MH  - Hospital Mortality
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Postoperative Complications/*mortality
MH  - Prosthesis Design
MH  - Reoperation
MH  - Survival Analysis
MH  - Treatment Outcome
EDAT- 2002/01/24 10:00
MHDA- 2002/03/07 10:01
CRDT- 2002/01/24 10:00
PHST- 2002/01/24 10:00 [pubmed]
PHST- 2002/03/07 10:01 [medline]
PHST- 2002/01/24 10:00 [entrez]
AID - astcs013b0136 [pii]
PST - ppublish
SO  - Semin Thorac Cardiovasc Surg. 2001 Oct;13(4 Suppl 1):136-42.