PMID- 11810718
OWN - NLM
STAT- MEDLINE
DCOM- 20020228
LR  - 20061115
IS  - 1059-910X (Print)
IS  - 1059-910X (Linking)
VI  - 56
IP  - 2
DP  - 2002 Jan 15
TI  - Gene expression in the supraoptic nucleus.
PG  - 158-63
AB  - The magnocellular neurosecretory cells (MNCs) in the supraoptic nucleus (SON) 
      express multiple kinds of genes, including not only the classical hormones 
      arginine vasopressin (AVP) and oxytocin (OXT), but also other physiologically 
      active substances including neuropeptides, their receptors, and nitric oxide (NO) 
      synthase, the rate-limiting enzyme in the synthesis of NO under physiological 
      condition. For example, osmotic stimuli such as dehydration and chronic salt 
      loading cause a wide range of changes of the expression levels of the genes and 
      marked induction of the expression of the genes in the SON. The expression of the 
      NO synthase gene in the SON under physiological conditions is reviewed.
CI  - Copyright 2002 Wiley-Liss, Inc.
FAU - Ueta, Yoichi
AU  - Ueta Y
AD  - Department of Physiology, School of Medicine, University of Occupational and 
      Environmental Health, Kitakyushu 807-8555, Japan. yoichi@med.uoeh-u.ac.jp
FAU - Levy, Andrew
AU  - Levy A
FAU - Lightman, Stafford L
AU  - Lightman SL
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Microsc Res Tech
JT  - Microscopy research and technique
JID - 9203012
RN  - 0 (RNA, Messenger)
RN  - 113-79-1 (Arginine Vasopressin)
RN  - 50-56-6 (Oxytocin)
RN  - EC 1.14.13.39 (Nitric Oxide Synthase)
SB  - IM
MH  - Animals
MH  - Arginine Vasopressin/genetics/metabolism
MH  - Gene Expression Regulation
MH  - Humans
MH  - In Situ Hybridization
MH  - Neurons/*metabolism
MH  - Nitric Oxide Synthase/genetics/metabolism
MH  - Oxytocin/genetics/metabolism
MH  - RNA, Messenger/analysis
MH  - Supraoptic Nucleus/cytology/*metabolism
RF  - 94
EDAT- 2002/01/26 10:00
MHDA- 2002/03/01 10:01
CRDT- 2002/01/26 10:00
PHST- 2002/01/26 10:00 [pubmed]
PHST- 2002/03/01 10:01 [medline]
PHST- 2002/01/26 10:00 [entrez]
AID - 10.1002/jemt.10020 [pii]
AID - 10.1002/jemt.10020 [doi]
PST - ppublish
SO  - Microsc Res Tech. 2002 Jan 15;56(2):158-63. doi: 10.1002/jemt.10020.