PMID- 11812335
OWN - NLM
STAT- MEDLINE
DCOM- 20020214
LR  - 20061115
IS  - 1002-0098 (Print)
IS  - 1002-0098 (Linking)
VI  - 36
IP  - 3
DP  - 2001 May
TI  - [A successive study of histopathological changes in unilateral facial muscle 
      denervation].
PG  - 177-9
AB  - OBJECTIVE: To observe the histopathological changes in unilateral facial muscle 
      denervation. METHODS: Gomori trichrome stain, acridine orange (AO) fluorescence, 
      enzyme-histochemistry and immunohistochemistry techniques were used for studying 
      mitochondria, nuclei acid concentration, enzymatic activity and contraction 
      protein expression of facial muscle in different denervation period. RESULTS: 
      Mitochondrian function, enzymatic activity and contraction protein expression of 
      facial muscle denervation increased in the first two weeks, then declined till 6 
      months. Myofiber's histotype began to transform in 1 month after denervation. 
      Type-grouping was obvious in 6 month. Regeneration myofibers were also seen at 
      this time. CONCLUSIONS: Unilateral facial muscles become atrophy after 
      denervation. They have proliferating tendency from 2 month to 6 month. Therefore, 
      within 1 month after denervation measures to benefit atrophy will be more 
      effective.
FAU - Xiao, R
AU  - Xiao R
AD  - Department of Oral Maxillofacial Surgery, Peking University School of 
      Stomatology, Beijing 100081, China.
FAU - Yu, G
AU  - Yu G
FAU - Jia, H
AU  - Jia H
LA  - chi
PT  - English Abstract
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - China
TA  - Zhonghua Kou Qiang Yi Xue Za Zhi
JT  - Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese 
      journal of stomatology
JID - 8711066
SB  - IM
MH  - Animals
MH  - Atrophy
MH  - *Denervation
MH  - Facial Muscles/chemistry/*innervation/*pathology
MH  - Immunohistochemistry
MH  - Male
MH  - Rabbits
EDAT- 2002/01/29 10:00
MHDA- 2002/02/15 10:01
CRDT- 2002/01/29 10:00
PHST- 2002/01/29 10:00 [pubmed]
PHST- 2002/02/15 10:01 [medline]
PHST- 2002/01/29 10:00 [entrez]
PST - ppublish
SO  - Zhonghua Kou Qiang Yi Xue Za Zhi. 2001 May;36(3):177-9.