PMID- 11814090
OWN - NLM
STAT- MEDLINE
DCOM- 20020711
LR  - 20190916
IS  - 1058-2916 (Print)
IS  - 1058-2916 (Linking)
VI  - 48
IP  - 1
DP  - 2002 Jan-Feb
TI  - New advances in dynamic cardiomyoplasty: Doppler flow wire shows improved cardiac 
      assistance in demand protocol.
PG  - 119-23
AB  - No data have been published on real cardiac assistance with demand dynamic 
      cardiomyoplasty. We tested the utility of a Doppler flow wire in measuring beat 
      by beat aortic flow velocity and evaluating cardiac assistance in demand 
      cardiomyoplasty patients. The technique was tested in seven patients (M/W = 6/1; 
      age, 57.1+/-6.2 years; atrial fibrillation/ sinus rhythm = 1/6; New York Heart 
      Association [NYHA] classification = 1.4+/-0.5). Measurements were done using a 
      0.018 inch peripheral Doppler flow wire advanced through a 5 French arterial 
      femoral sheath. Three 1 minute periods with the stimulator off, and three 1 
      minute periods with clinical stimulation were recorded. We measured peak aortic 
      flow velocity in all beats. Latissimus dorsi mechanogram was simultaneously 
      recorded. Comparison between preoperative and follow-up data showed significantly 
      higher values of tetanic fusion frequency and ejection fraction at follow-up, 
      whereas mean NYHA class was significantly lower. Statistical analysis showed an 
      increase in aortic flow velocity not only in the assisted versus rest period, but 
      also in assisted versus unassisted beats (8.42+/-6.98% and 7.55+/-3.07%). A 
      linear correlation was found between increase in flow velocity and latissimus 
      dorsi wrap tetanic fusion frequency (r2 = 0.53). In demand dynamic 
      cardiomyoplasty, systolic assistance is significant and correlated to the 
      latissimus dorsi speed of contraction; a demand stimulation protocol maintains 
      muscle properties and increases muscle performance.
FAU - Rigatelli, Gianluca
AU  - Rigatelli G
AD  - Department of Cardiology, Legnago General Hospital, Verona, Italy.
FAU - Carraro, Ugo
AU  - Carraro U
FAU - Barbiero, Mario
AU  - Barbiero M
FAU - Zanchetta, Mario
AU  - Zanchetta M
FAU - Pedon, Luigi
AU  - Pedon L
FAU - Dimopoulos, Konstantinos
AU  - Dimopoulos K
FAU - Rigatelli, Giorgio
AU  - Rigatelli G
FAU - Maiolino, Pietro
AU  - Maiolino P
FAU - Cobelli, Franco
AU  - Cobelli F
FAU - Riccardi, Riccardo
AU  - Riccardi R
FAU - Volta, Sergio Dalla
AU  - Volta SD
LA  - eng
PT  - Clinical Trial
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - ASAIO J
JT  - ASAIO journal (American Society for Artificial Internal Organs : 1992)
JID - 9204109
SB  - IM
MH  - Aged
MH  - Aorta/diagnostic imaging/physiology
MH  - Blood Flow Velocity
MH  - Cardiomyoplasty/*instrumentation/*trends
MH  - Diastole
MH  - Female
MH  - Humans
MH  - Laser-Doppler Flowmetry
MH  - Male
MH  - Middle Aged
MH  - Systole
MH  - Ultrasonography
EDAT- 2002/01/30 10:00
MHDA- 2002/07/12 10:01
CRDT- 2002/01/30 10:00
PHST- 2002/01/30 10:00 [pubmed]
PHST- 2002/07/12 10:01 [medline]
PHST- 2002/01/30 10:00 [entrez]
AID - 10.1097/00002480-200201000-00025 [doi]
PST - ppublish
SO  - ASAIO J. 2002 Jan-Feb;48(1):119-23. doi: 10.1097/00002480-200201000-00025.