PMID- 11816293
OWN - NLM
STAT- MEDLINE
DCOM- 20020221
LR  - 20061115
IS  - 0043-5147 (Print)
IS  - 0043-5147 (Linking)
VI  - 54
IP  - 9-10
DP  - 2001
TI  - [The influence of thyroidectomy of serum VEGF levels in patients with Graves 
      disease].
PG  - 504-7
AB  - Angiogenic cytokines, including vascular endothelial growth factor (VEGF), play 
      an important role in patients after surgery because they facilitate proper wound 
      healing. The aim of the paper was the comparison of serum VEGF levels in patients 
      before and after thyroidectomy due to Graves disease (Gd). A serum VEGF level was 
      determined by means of ELISA method before the operation as well as 3 and 7 days 
      after it in 24 patients. The mean serum VEGF level was 61.2 pg/ml (range, 
      33.7-105.0 pg/ml) before the operation and increased after the operation to 115.6 
      pg/ml (range, 36.3-214.2 pg/ml). After thyroidectomy, the mean level of serum 
      VEGF level in all patients rose by for 79.5% (range, 7.7-115.4%). These results 
      suggest that serum VEGF level increases in patients with Gd after subtotal 
      thyroidectomy, although disorder in secreting cytokines is observed in Gd 
      patients and they were administered thyrostatics up to the operation, which have 
      an immunosuppressive activity.
FAU - Kolomecki, K
AU  - Kolomecki K
AD  - Klinika Chirurgii Endokrynologicznej i Ogolnej Akademii Medycznej w Lodzi. 
      branch@poczta.onet.pl
FAU - Bartos, M
AU  - Bartos M
FAU - Pomorski, L
AU  - Pomorski L
FAU - Kuzdak, K
AU  - Kuzdak K
LA  - pol
PT  - English Abstract
PT  - Journal Article
TT  - Wplyw strumektomii na stezenie VEGF w surowicy krwi u chorych z choroba 
      Gravesa-Basedowa.
PL  - Poland
TA  - Wiad Lek
JT  - Wiadomosci lekarskie (Warsaw, Poland : 1960)
JID - 9705467
RN  - 0 (Endothelial Growth Factors)
RN  - 0 (Lymphokines)
RN  - 0 (Vascular Endothelial Growth Factor A)
RN  - 0 (Vascular Endothelial Growth Factors)
SB  - IM
MH  - Adult
MH  - Case-Control Studies
MH  - Endothelial Growth Factors/*blood
MH  - Enzyme-Linked Immunosorbent Assay
MH  - Female
MH  - Graves Disease/*blood/*surgery
MH  - Humans
MH  - Lymphokines/*blood
MH  - Middle Aged
MH  - *Thyroidectomy
MH  - Time Factors
MH  - Vascular Endothelial Growth Factor A
MH  - Vascular Endothelial Growth Factors
MH  - Wound Healing
EDAT- 2002/01/31 10:00
MHDA- 2002/02/22 10:01
CRDT- 2002/01/31 10:00
PHST- 2002/01/31 10:00 [pubmed]
PHST- 2002/02/22 10:01 [medline]
PHST- 2002/01/31 10:00 [entrez]
PST - ppublish
SO  - Wiad Lek. 2001;54(9-10):504-7.