PMID- 11823923
OWN - NLM
STAT- MEDLINE
DCOM- 20020422
LR  - 20191210
IS  - 0720-4299 (Print)
IS  - 0720-4299 (Linking)
VI  - 70
IP  - 2
DP  - 2002 Feb
TI  - [Influence of treatment with acetyl-cholinesterase inhibitors on 
      psychopathological symptoms in Alzheimer's disease].
PG  - 78-83
AB  - The treatment of the cognitive deficits has been the major focus in patients with 
      Alzheimer's disease (DAT) so far. Recently there is increasing interest in 
      Behavioral and Psychological Symptoms of Dementia (BPSD), which can place much 
      burden on DAT patients and their caregivers. With the introduction of 
      Acetylcholinesterase Inhibitors (AChEI) of the second generation the therapeutic 
      armament has been extended. The clinical evaluation of AChEI has found growing 
      evidence that these compounds do not only improve cognitive abilities and 
      activities of daily living (ADL), but also BPSD. The given data regarding the 
      three AChEI available on the market allow the conclusion that there is a general 
      improvement in BPSD. Beside these particularly positive effects on 
      hallucinations, mood symptoms, aggressiveness, and agitation seem possible but 
      need further clarification.
FAU - Rosler, M
AU  - Rosler M
AD  - Arbeitsgruppe Gerontopsychiatrie, Universitatskliniken des Saarlandes, Homburg, 
      Germany.
FAU - Frey, U
AU  - Frey U
LA  - ger
PT  - Evaluation Study
PT  - Journal Article
PT  - Review
TT  - Einfluss der Therapie mit Azetyl-Cholinesterase-Inhibitoren (AChEI) auf 
      psychopathologische Symptome bei der Alzheimer-Krankheit.
PL  - Germany
TA  - Fortschr Neurol Psychiatr
JT  - Fortschritte der Neurologie-Psychiatrie
JID - 8103137
RN  - 0 (Cholinesterase Inhibitors)
SB  - IM
MH  - Activities of Daily Living/psychology
MH  - Aged
MH  - Alzheimer Disease/diagnosis/*drug therapy/psychology
MH  - Cholinesterase Inhibitors/adverse effects/*therapeutic use
MH  - Humans
MH  - Neuropsychological Tests
MH  - Social Behavior
MH  - Treatment Outcome
RF  - 61
EDAT- 2002/02/02 10:00
MHDA- 2002/04/23 10:01
CRDT- 2002/02/02 10:00
PHST- 2002/02/02 10:00 [pubmed]
PHST- 2002/04/23 10:01 [medline]
PHST- 2002/02/02 10:00 [entrez]
AID - 10.1055/s-2002-19920 [doi]
PST - ppublish
SO  - Fortschr Neurol Psychiatr. 2002 Feb;70(2):78-83. doi: 10.1055/s-2002-19920.