PMID- 1182945
OWN - NLM
STAT- MEDLINE
DCOM- 19760130
LR  - 20190623
IS  - 0009-7322 (Print)
IS  - 0009-7322 (Linking)
VI  - 52
IP  - 6
DP  - 1975 Dec
TI  - Ventricular arrhythmias in the late hospital phase of acute myocardial 
      infarction. Relation to left ventricular function detected by gated cardiac blood 
      pool scanning.
PG  - 1006-11
AB  - Abnormalities of left ventricular function and extent of myocardial infarction 
      were studied in relation to prevalence of late ventricular premature contractions 
      (VPCs) in 36 patients in the convalescent stage of acute myocardial infarction 
      (MI). Left ventricular ejection fraction (EF) and percent akinesis (%A) were 
      calculated from gated cardiac blood pool scans; myocardial infarct size was 
      estimated from peak CPK values; and VPCs were detected by 24 hour ambulatory ECGs 
      2-4 weeks following hospitalization for acute MI. Twenty-two patients had either 
      zero (class 0) or less than 30/hour unifocal VPCs (class I). Fourteen patients 
      had greater than 30/hour unifocal (class II), multifocal (class III) or coupled 
      VPCs (class IV), including ventricular tachycardia. Thirteen of 14 class II-IV 
      patients had EF less than 40% compared with only 8 of 22 class 0-I patients. 
      Class II-IV patients had significantly lower mean EF (30.5 +/- 2.3 SE to 49.6 +/- 
      4.0) P less than 0.01, higher mean %A (28.1 +/- 2.2 to 16.9 +/- 3.7) P less than 
      0.05, and higher mean peak CPK (1350 +/- 187 to 721 +/- 155) P less than 0.05 
      than class 0-I patients. These data suggest that VPCs may not be an independent 
      risk factor for sudden cardiac death in the convalescent phase of MI.
FAU - Schulze, R A Jr
AU  - Schulze RA Jr
FAU - Rouleau, J
AU  - Rouleau J
FAU - Rigo, P
AU  - Rigo P
FAU - Bowers, S
AU  - Bowers S
FAU - Strauss, H W
AU  - Strauss HW
FAU - Pitt, B
AU  - Pitt B
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Circulation
JT  - Circulation
JID - 0147763
SB  - IM
MH  - Acute Disease
MH  - Arrhythmias, Cardiac/*physiopathology
MH  - Convalescence
MH  - Death, Sudden
MH  - Electrocardiography
MH  - Heart Ventricles/*physiopathology
MH  - Hospitalization
MH  - Humans
MH  - Myocardial Contraction
MH  - Myocardial Infarction/mortality/*physiopathology
EDAT- 1975/12/11 19:15
MHDA- 2001/03/28 10:01
CRDT- 1975/12/11 19:15
PHST- 1975/12/11 19:15 [pubmed]
PHST- 2001/03/28 10:01 [medline]
PHST- 1975/12/11 19:15 [entrez]
AID - 10.1161/01.cir.52.6.1006 [doi]
PST - ppublish
SO  - Circulation. 1975 Dec;52(6):1006-11. doi: 10.1161/01.cir.52.6.1006.