PMID- 11836843
OWN - NLM
STAT- MEDLINE
DCOM- 20020426
LR  - 20131121
IS  - 0896-5846 (Print)
IS  - 0896-5846 (Linking)
VI  - 24
IP  - 1
DP  - 2001 Jan-Feb
TI  - Central venous catheters for infusion therapy in gastrointestinal cancer. A 
      comparative study of tunnelled centrally placed catheters and peripherally 
      inserted central catheters.
PG  - 38-47
AB  - Protracted venous infusion of 5-fluorouracil (5-FU) is a common treatment for 
      patients with gastrointestinal malignancy. A central venous access device is 
      required for safe and effective drug delivery. This study uses a survival 
      analysis to compare the useful life and treatment completion success of tunelled 
      centrally placed catheters (TCPCs) and peripherally inserted central catheters 
      (PICCs). It also describes complications found with both devices. Data on 
      insertion, complications, and removal of TCPCs and PICCs were collected on 
      standardized forms, prospectively for initial PICCs and retrospectively for 
      initial TCPCs. Survival of indwelling catheters was similar for both devices for 
      the first 120 days, but after that TCPC survival was statistically better than 
      that of PICCs (P = 0.051). Complications occurred in 61% of patients with TCPCs 
      and 67% of patients with PICCs. The authors conclude that PICCs provide less 
      invasive, more cost-effective, and easier to schedule central venous access for 
      5-FU infusion; however, their advantage over TCPCs decreases significantly in 
      treatments lasting more than 120 days.
FAU - Snelling, R
AU  - Snelling R
AD  - Hamilton Regional Cancer Center.
FAU - Jones, G
AU  - Jones G
FAU - Figueredo, A
AU  - Figueredo A
FAU - Major, P
AU  - Major P
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - United States
TA  - J Intraven Nurs
JT  - Journal of intravenous nursing : the official publication of the Intravenous 
      Nurses Society
JID - 8804311
RN  - 0 (Antimetabolites, Antineoplastic)
RN  - U3P01618RT (Fluorouracil)
MH  - Antimetabolites, Antineoplastic/administration & dosage
MH  - Catheterization, Central Venous/adverse 
      effects/economics/*instrumentation/methods
MH  - Catheterization, Peripheral/adverse effects/economics/*instrumentation/methods
MH  - Catheters, Indwelling/adverse effects/economics/*standards
MH  - Clinical Nursing Research
MH  - Cost-Benefit Analysis
MH  - Equipment Design
MH  - Fluorouracil/administration & dosage
MH  - Gastrointestinal Neoplasms/*drug therapy
MH  - Humans
MH  - Infusions, Intravenous/adverse effects/economics/*instrumentation/*methods
MH  - Pain/epidemiology/etiology
MH  - Phlebitis/epidemiology/etiology
MH  - Proportional Hazards Models
MH  - Prospective Studies
MH  - Retrospective Studies
MH  - Survival Analysis
MH  - Time Factors
MH  - Treatment Outcome
MH  - Wound Infection/epidemiology/etiology
EDAT- 2002/02/12 10:00
MHDA- 2002/04/27 10:01
CRDT- 2002/02/12 10:00
PHST- 2002/02/12 10:00 [pubmed]
PHST- 2002/04/27 10:01 [medline]
PHST- 2002/02/12 10:00 [entrez]
PST - ppublish
SO  - J Intraven Nurs. 2001 Jan-Feb;24(1):38-47.