PMID- 11855083
OWN - NLM
STAT- MEDLINE
DCOM- 20020226
LR  - 20201208
IS  - 1343-3490 (Print)
IS  - 1343-3490 (Linking)
VI  - 39
IP  - 11
DP  - 2001 Nov
TI  - [A case of ankylosing spondylitis associated with pulmonary aspergillosis and 
      amyloidosis].
PG  - 847-51
AB  - A 56-year-old man was admitted because of diarrhea, cough, weight loss, and 
      disturbance of consciousness. He had been diagnosed as having ankylosing 
      spondylitis at 18-years old. The spondylitis progressed until there was complete 
      rigidity of the spine including the neck, hip and knee joints. Human leukocyte 
      antigen (HLA) B27, which has been characteristic of ankylosing spondylitis, was 
      also present in this case. A chest radiograph showed pleural thickness and a 
      cavity in the right upper lobe; and a soft tissue mass and fluid level was found 
      in the cavity. Aspergillus fumigatus was detected in the sputum and pulmonary 
      aspergillosis was diagnosed. Biopsy of the colon revealed that a large 
      interstitial amyloidosis. Despite the treatment of the patient's malnutrition and 
      lung aspergillosis using amphotericin B, the clinical course was rapidly 
      progressive and the patient died of respiratory failure due to lung 
      aspergillosis. It is important to be aware of these rare complications, which are 
      correlated with the prognosis in cases of ankylosing spondylitis.
FAU - Tokimatsu, I
AU  - Tokimatsu I
AD  - Third Department of Internal Medicine, Oita Prefectural Hospital, 476 Bunyou, 
      Oita, Oita 870-0855, Japan.
FAU - Uenishi, Y
AU  - Uenishi Y
FAU - Nakama, K
AU  - Nakama K
FAU - Yamasaki, T
AU  - Yamasaki T
FAU - Miyazaki, T
AU  - Miyazaki T
FAU - Nasu, M
AU  - Nasu M
LA  - jpn
PT  - Case Reports
PT  - Journal Article
PL  - Japan
TA  - Nihon Kokyuki Gakkai Zasshi
JT  - Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society
JID - 9808802
SB  - IM
MH  - Amyloidosis/*etiology
MH  - Aspergillosis/*etiology
MH  - *Aspergillus fumigatus
MH  - Humans
MH  - Lung Diseases, Fungal/*etiology
MH  - Male
MH  - Middle Aged
MH  - Spondylitis, Ankylosing/*complications
EDAT- 2002/02/22 10:00
MHDA- 2002/02/28 10:01
CRDT- 2002/02/22 10:00
PHST- 2002/02/22 10:00 [pubmed]
PHST- 2002/02/28 10:01 [medline]
PHST- 2002/02/22 10:00 [entrez]
PST - ppublish
SO  - Nihon Kokyuki Gakkai Zasshi. 2001 Nov;39(11):847-51.