PMID- 11855785
OWN - NLM
STAT- MEDLINE
DCOM- 20030725
LR  - 20191105
IS  - 0017-6559 (Print)
IS  - 0017-6559 (Linking)
VI  - 31
IP  - 3
DP  - 2001
TI  - Analysis of IL-18 bioactivity and IL-18 mRNA in three patients with adult T-cell 
      leukaemia, acute mixed lineage leukaemia, and acute lymphocytic leukaemia 
      accompanied with high serum IL-18 levels.
PG  - 231-5
AB  - Interleukin-18 (IL-18) bioactivity in sera and IL-18 mRNA expression in leukaemia 
      cells of three patients with adult T-cell leukaemia (ATL), acute mixed lineage 
      leukaemia (AMLL) and acute lymphocytic leukaemia (ALL) accompanied with high 
      serum IL-18 levels have been analysed. There was little serum IL-18 bioactivity 
      in the three patients with ATL, AMLL and ALL, while IL-18 mRNA expression was 
      detected in leukaemia cells of all three patients.
FAU - Takubo, T
AU  - Takubo T
AD  - Clinical Hematology and Clinical Diagnostics, Graduate School of Medicine, Osaka 
      City University, Japan. m3542254@med.osaka-cu.ac.jp
FAU - Kumura, T
AU  - Kumura T
FAU - Kanashima, H
AU  - Kanashima H
FAU - Nakao, T
AU  - Nakao T
FAU - Nakamae, H
AU  - Nakamae H
FAU - Aoyama, Y
AU  - Aoyama Y
FAU - Yamamura, R
AU  - Yamamura R
FAU - Ohta, T
AU  - Ohta T
FAU - Koh, K R
AU  - Koh KR
FAU - Ohta, K
AU  - Ohta K
FAU - Yamane, T
AU  - Yamane T
FAU - Hino, M
AU  - Hino M
FAU - Kamitani, T
AU  - Kamitani T
FAU - Tatsumi, N
AU  - Tatsumi N
LA  - eng
PT  - Journal Article
PL  - Netherlands
TA  - Haematologia (Budap)
JT  - Haematologia
JID - 0130266
RN  - 0 (Interleukin-18)
RN  - 0 (RNA, Messenger)
RN  - 82115-62-6 (Interferon-gamma)
SB  - IM
MH  - Acute Disease
MH  - Aged
MH  - Case-Control Studies
MH  - Dose-Response Relationship, Drug
MH  - Female
MH  - Humans
MH  - Interferon-gamma/biosynthesis/drug effects
MH  - Interleukin-18/blood/genetics/*physiology
MH  - Leukemia/*blood/metabolism
MH  - Leukemia-Lymphoma, Adult T-Cell/blood/metabolism
MH  - Male
MH  - Middle Aged
MH  - Precursor Cell Lymphoblastic Leukemia-Lymphoma/blood/metabolism
MH  - RNA, Messenger/*metabolism
MH  - Tumor Cells, Cultured/drug effects
EDAT- 2002/02/22 10:00
MHDA- 2003/07/26 05:00
CRDT- 2002/02/22 10:00
PHST- 2002/02/22 10:00 [pubmed]
PHST- 2003/07/26 05:00 [medline]
PHST- 2002/02/22 10:00 [entrez]
AID - 10.1163/15685590152763773 [doi]
PST - ppublish
SO  - Haematologia (Budap). 2001;31(3):231-5. doi: 10.1163/15685590152763773.