PMID- 11858176 OWN - NLM STAT- MEDLINE DCOM- 20020722 LR - 20191105 IS - 1522-7952 (Print) IS - 1522-7952 (Linking) VI - 21 IP - 1 DP - 2002 Jan-Feb TI - Maternal pulmonary adenocarcinoma metastatic to the fetus: first recorded case report and literature review. PG - 57-69 AB - We report the first maternal pulmonary adenocarcinoma metastatic to the fetus as well as an updated literature review. Review of the literature revealed that there have been only 67 cases of maternal malignancy metastatic to the products of conception. These were mostly malignant melanoma and hematopoietic tumors. A 46-year old multiparous woman with metastatic pulmonary adenocarcinoma, diagnosed at 23 weeks gestation, delivered a male infant who appeared normal at birth. The mother died 2 days after delivery. The child developed multiple scalp tumors a 2 weeks of age. The tumors recurred rapidly after initial resection. Wide local excision of the involved scalp and skin graft coverage was performed at 14 weeks of age. Histopathology of these tumors was identical to that of the maternal tumor. The maternal origin of these tumors was confirmed by fluorescence in situ hybridization (FISH). The child is now 5 years old and free of disease. FAU - Walker, John W T AU - Walker JW AD - Division of Plastic Surgery, Childrens Hospital Los Angeles-University of Southern California, Keck School of Medicine, 90027, USA. jwalker@chla.usc.edu FAU - Reinisch, John F AU - Reinisch JF FAU - Monforte, Hector L AU - Monforte HL LA - eng PT - Case Reports PT - Journal Article PT - Review PL - United States TA - Pediatr Pathol Mol Med JT - Pediatric pathology & molecular medicine JID - 100885435 SB - IM MH - Adenocarcinoma/*diagnosis/mortality/*pathology MH - Female MH - Hematologic Neoplasms/diagnosis/pathology MH - Humans MH - In Situ Hybridization, Fluorescence MH - Infant, Newborn MH - Lung Neoplasms/*diagnosis/mortality/*pathology MH - Male MH - Melanoma/diagnosis/pathology MH - Middle Aged MH - Neoplasm Metastasis MH - Pregnancy MH - Pregnancy Complications, Neoplastic/*diagnosis/surgery MH - Scalp MH - Skin Neoplasms/*secondary/surgery RF - 30 EDAT- 2002/02/23 10:00 MHDA- 2002/07/23 10:01 CRDT- 2002/02/23 10:00 PHST- 2002/02/23 10:00 [pubmed] PHST- 2002/07/23 10:01 [medline] PHST- 2002/02/23 10:00 [entrez] AID - 10.1080/pdp.21.1.57.69 [doi] PST - ppublish SO - Pediatr Pathol Mol Med. 2002 Jan-Feb;21(1):57-69. doi: 10.1080/pdp.21.1.57.69.