PMID- 11894738
OWN - NLM
STAT- MEDLINE
DCOM- 20020821
LR  - 20161020
IS  - 1088-5412 (Print)
IS  - 1088-5412 (Linking)
VI  - 23
IP  - 1
DP  - 2002 Jan-Feb
TI  - Effects of air pollutants on the allergic response.
PG  - 9-14
AB  - There is strong evidence that the prevalence and severity of allergy are 
      increasing in many areas of the world. Pollutants have been implicated as one of 
      the important factors responsible for these observations because they have been 
      shown to act at multiple steps in the allergic response. They can increase 
      immunoglobulin E (IgE) synthesis and potentiate the specific IgE response to 
      antigens. Pollutants also are capable of inducing a primary specific IgE response 
      to an antigen and increase allergic airway inflammation. In addition, pollutants 
      can induce airway inflammation or cause nonspecific irritation. Pollutants also 
      are capable of modulating the allergenicity of airborne substances, which 
      possibly may promote allergic sensitization.
FAU - Patton, Lucinda
AU  - Patton L
AD  - Department of Medicine, Section of Clinical Immunology, Allergy and Rheumatology, 
      Tulane University Health Sciences Center, 1700 Perdido Street (SL-57), New 
      Orleans, LA 70112, USA.
FAU - Lopez, Manuel
AU  - Lopez M
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Allergy Asthma Proc
JT  - Allergy and asthma proceedings
JID - 9603640
RN  - 0 (Air Pollutants)
SB  - IM
MH  - Air Pollutants/*adverse effects/immunology
MH  - Humans
MH  - Hypersensitivity/*etiology/immunology
RF  - 50
EDAT- 2002/03/16 10:00
MHDA- 2002/08/22 10:01
CRDT- 2002/03/16 10:00
PHST- 2002/03/16 10:00 [pubmed]
PHST- 2002/08/22 10:01 [medline]
PHST- 2002/03/16 10:00 [entrez]
PST - ppublish
SO  - Allergy Asthma Proc. 2002 Jan-Feb;23(1):9-14.