PMID- 11894982
OWN - NLM
STAT- MEDLINE
DCOM- 20020326
LR  - 20190813
IS  - 0300-0664 (Print)
IS  - 0300-0664 (Linking)
VI  - 55
IP  - 5
DP  - 2001 Nov
TI  - Malignant thymic carcinoid is not prevented by transcervical thymectomy in 
      multiple endocrine neoplasia type 1.
PG  - 689-93
AB  - Multiple endocrine neoplasia type 1 (MEN 1) is an autosomal dominant tumour 
      syndrome. It is characterized by primary hyperparathyroidism, pituitary neoplasia 
      and foregut lineage neuroendocrine neoplasia. Malignant thymic carcinoid tumours 
      are an uncommon but important manifestation of MEN 1. Transcervical thymectomy is 
      often advocated as prophylaxis against thymic carcinoids, although there is a 
      paucity of evidence to support the efficacy of this procedure. This is the first 
      report of a malignant thymic carcinoid occurring in an MEN 1 patient following 
      prior parathyroidectomy and transcervical thymectomy. It is concluded that 
      transcervical thymectomy does not reliably provide prophylaxis against thymic 
      carcinoid.
FAU - Burgess, J R
AU  - Burgess JR
AD  - Department of Diabetes, Royal Hobart Hospital, Tasmania, Australia. 
      jburgess@postoffice.utas.edu.au
FAU - Giles, N
AU  - Giles N
FAU - Shepherd, J J
AU  - Shepherd JJ
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - England
TA  - Clin Endocrinol (Oxf)
JT  - Clinical endocrinology
JID - 0346653
RN  - RWM8CCW8GP (Octreotide)
SB  - IM
MH  - Adolescent
MH  - Carcinoid Tumor/*prevention & control/surgery
MH  - Humans
MH  - Male
MH  - Multiple Endocrine Neoplasia Type 1/*surgery
MH  - Octreotide
MH  - Parathyroidectomy
MH  - *Thymectomy
MH  - Thymus Neoplasms/*prevention & control/surgery
MH  - Treatment Failure
EDAT- 2002/03/16 10:00
MHDA- 2002/03/27 10:01
CRDT- 2002/03/16 10:00
PHST- 2002/03/16 10:00 [pubmed]
PHST- 2002/03/27 10:01 [medline]
PHST- 2002/03/16 10:00 [entrez]
AID - 1348 [pii]
AID - 10.1046/j.1365-2265.2001.01348.x [doi]
PST - ppublish
SO  - Clin Endocrinol (Oxf). 2001 Nov;55(5):689-93. doi: 
      10.1046/j.1365-2265.2001.01348.x.