PMID- 11900324 OWN - NLM STAT- MEDLINE DCOM- 20020911 LR - 20190607 IS - 0144-8463 (Print) IS - 0144-8463 (Linking) VI - 21 IP - 4 DP - 2001 Aug TI - Laser refractive surgery: technological advance and tissue response. PG - 491-512 AB - Photorefractive keratectomy (PRK) and laser assisted in situ keratomileusis (LASIK), using an excimer laser, are the currently popular techniques of correcting refractive errors. Since these techniques work by selective ablation of corneal stroma, the tissue healing response plays a great role in the ultimate outcome of surgery. Also, various methods of wound healing modulation can be used to achieve better results. While these procedures do lead to a decrease in dioptric power and increase in unaided visual acuity, higher visual functions like contrast sensitivity can sometimes be compromised after the surgery. FAU - Bansal, A K AU - Bansal AK AD - L. V. Prasad Eye Institute, L. V. Prasad Marg, Banjara Hills, Hyderabad, India. akb@Ivpeye.stph.net FAU - Veenashree, M P AU - Veenashree MP LA - eng PT - Journal Article PT - Review PL - England TA - Biosci Rep JT - Bioscience reports JID - 8102797 SB - IM MH - Corneal Injuries MH - DNA Damage MH - Endothelium/injuries MH - Epithelium/injuries MH - Humans MH - *Keratomileusis, Laser In Situ/adverse effects/methods MH - Lasers MH - Lasers, Excimer MH - *Photorefractive Keratectomy/adverse effects/methods MH - Refractive Errors/physiopathology MH - *Refractive Surgical Procedures MH - Tears/physiology MH - Wound Healing RF - 162 EDAT- 2002/03/20 10:00 MHDA- 2002/09/12 10:01 CRDT- 2002/03/20 10:00 PHST- 2002/03/20 10:00 [pubmed] PHST- 2002/09/12 10:01 [medline] PHST- 2002/03/20 10:00 [entrez] AID - 10.1023/a:1017947927593 [doi] PST - ppublish SO - Biosci Rep. 2001 Aug;21(4):491-512. doi: 10.1023/a:1017947927593.