PMID- 11905937
OWN - NLM
STAT- MEDLINE
DCOM- 20021002
LR  - 20191105
IS  - 1440-2440 (Print)
IS  - 1878-1861 (Linking)
VI  - 4
IP  - 4
DP  - 2001 Dec
TI  - Influence of weight training exercise and modification of hormonal response on 
      skeletal muscle growth.
PG  - 431-46
AB  - To investigate the influence of carbohydrate (CHO) consumption on the acute 
      hormonal response, and chronic adaptation to weight lifting exercise, two studies 
      were conducted. Following a four-hour fast, seven young men (21.3 +/- 3.5 y) 
      performed (on two occasions) a nine-station weight lifting protocol, completing 3 
      sets of 10 repetitions at 75% of 1RM (series 1). Randomly assigned, one session 
      included the ingestion of a non-caloric placebo, and the other, a 6% CHO 
      solution. For series 2, two groups of young men (21.3 +/- 1.5 y) participated in 
      12 weeks of progressive resistance weight training. Training for one group 
      included the ingestion of a non-caloric placebo, and the other, a 6% CHO 
      solution. In series 1, weight lifting exercise with CHO ingestion significantly 
      (p < 0.05) elevated blood glucose and plasma insulin levels above baseline, as 
      well as that occurring with the placebo. This resulted in a significant blunting 
      of the cortisol response (7% with CHO compared to 99% with placebo). These 
      findings indicate that CHO consumption during weight lifting exercise can modify 
      the acute hormonal response to exercise. With series 2, CHO consumption continued 
      to blunt the cortisol response to exercise during the twelve weeks of training. 
      This is in contrast to significantly elevated cortisol levels observed for the 
      placebo control group. Corresponding with the modified response patterns were 
      differences in muscle growth. Weight training exercise with CHO ingestion 
      resulted in significantly greater gains in both type I (19.1%) and type II 
      (22.5%) muscle fibre area than weight training exercise alone. The difference in 
      the cortisol response accounted for 74% of the variance (r = 0.8579, p = 0.006) 
      of change in type I muscle fibre area, and 52.3% of the variance (r = 0.7231, p = 
      0.043) of change in type II muscle fibre area. These findings suggest that the 
      modification of the cortisol response associated with CHO ingestion can 
      positively impact the skeletal muscle hypertrophic adaptation to weigh training.
FAU - Tarpenning, K M
AU  - Tarpenning KM
AD  - Department of Exercise Sciences, Uniersity of Southern California, Los Angeles, 
      USA.
FAU - Wiswell, R A
AU  - Wiswell RA
FAU - Hawkins, S A
AU  - Hawkins SA
FAU - Marcell, T J
AU  - Marcell TJ
LA  - eng
PT  - Clinical Trial
PT  - Journal Article
PT  - Randomized Controlled Trial
PL  - Australia
TA  - J Sci Med Sport
JT  - Journal of science and medicine in sport
JID - 9812598
RN  - 0 (Blood Glucose)
RN  - 0 (Dietary Carbohydrates)
RN  - 0 (Insulin)
RN  - WI4X0X7BPJ (Hydrocortisone)
SB  - IM
MH  - *Adaptation, Physiological
MH  - Adult
MH  - Analysis of Variance
MH  - Biopsy
MH  - Blood Glucose/analysis
MH  - Body Composition
MH  - Dietary Carbohydrates/*administration & dosage/metabolism
MH  - Humans
MH  - Hydrocortisone/blood
MH  - Insulin/blood
MH  - Leg/physiology
MH  - Male
MH  - Muscle, Skeletal/metabolism/*physiology
MH  - Physical Education and Training
MH  - Weight Lifting/*physiology
EDAT- 2002/03/22 10:00
MHDA- 2002/10/03 04:00
CRDT- 2002/03/22 10:00
PHST- 2002/03/22 10:00 [pubmed]
PHST- 2002/10/03 04:00 [medline]
PHST- 2002/03/22 10:00 [entrez]
AID - S1440-2440(01)80052-9 [pii]
AID - 10.1016/s1440-2440(01)80052-9 [doi]
PST - ppublish
SO  - J Sci Med Sport. 2001 Dec;4(4):431-46. doi: 10.1016/s1440-2440(01)80052-9.