PMID- 11908728
OWN - NLM
STAT- MEDLINE
DCOM- 20030729
LR  - 20190116
IS  - 1042-8194 (Print)
IS  - 1026-8022 (Linking)
VI  - 43
IP  - 1
DP  - 2002 Jan
TI  - Simultaneous occurrence of myelodysplastic syndrome and monoclonal B lymphocytes 
      with a different clonal origin.
PG  - 191-3
AB  - Bone marrow and peripheral blood from a myelodysplastic syndrome patient with 
      trisomy 13 and monoclonal B lymphocytes (without evidence of systemic lymphoma) 
      were investigated for clonal lymphoid lineage involvement using interphase 
      fluorescence in situ hybridization (FISH) and X-chromosome inactivation assay 
      (HUMARA) on CD19+ and CD34+ sorted cells. Trisomy 13 was detected in 55% of CD34+ 
      cells and in 5.5% of CD19+ cells, the latter being comparable to the negative 
      control specimen. X-chromosome inactivation showed both CD34+ and CD19+ cells to 
      be monoclonal, though their inactivated X-chromosome was different. The results 
      strongly suggested that both populations of CD34+ and CD19+ cells have originated 
      from a different progenitor stem cell.
FAU - Cauwelier, B
AU  - Cauwelier B
AD  - Laboratory of Haematology, AZ St. Jan AV, Bruges, Belgium.
FAU - Nollet, F
AU  - Nollet F
FAU - De Laere, E
AU  - De Laere E
FAU - Van Leeuwen, M
AU  - Van Leeuwen M
FAU - Billiet, J
AU  - Billiet J
FAU - Criel, A
AU  - Criel A
FAU - Louwagie, A
AU  - Louwagie A
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - United States
TA  - Leuk Lymphoma
JT  - Leukemia & lymphoma
JID - 9007422
SB  - IM
MH  - Aged
MH  - B-Lymphocytes/*pathology
MH  - Cell Lineage
MH  - Cell Transformation, Neoplastic/*pathology
MH  - Chromosomes, Human, Pair 13
MH  - Clone Cells/pathology
MH  - Cytogenetic Analysis
MH  - Female
MH  - Flow Cytometry
MH  - Humans
MH  - Myelodysplastic Syndromes/*pathology
MH  - Trisomy
EDAT- 2002/03/23 10:00
MHDA- 2003/07/30 05:00
CRDT- 2002/03/23 10:00
PHST- 2002/03/23 10:00 [pubmed]
PHST- 2003/07/30 05:00 [medline]
PHST- 2002/03/23 10:00 [entrez]
AID - 10.1080/10428190210205 [doi]
PST - ppublish
SO  - Leuk Lymphoma. 2002 Jan;43(1):191-3. doi: 10.1080/10428190210205.