PMID- 11911528 OWN - NLM STAT- MEDLINE DCOM- 20021018 LR - 20190901 IS - 0269-7491 (Print) IS - 0269-7491 (Linking) VI - 117 IP - 3 DP - 2002 TI - Persistent chlorinated pesticides and polychlorinated biphenyls in selected fish species from Lake Tanganyika, Burundi, Africa. PG - 447-55 AB - Concentrations of selected organochlorine pesticides and PCBs in seven fish species (cichlids) from the north end of the Lake Tanganyika, Burundi, Africa were determined. Results were compared to previous work on the Lake Tanganyika and other water bodies and to the European Community maximum residue levels (MRLs) in edible fat. The analytical method included a hot Soxhlet extraction with a mixture of acetone: hexane (1:3, v/v), gravimetrically lipid determination, and a single step clean-up. For PCBs and stable pesticides, the clean-up was done on activated silica gel impregnated with concentrated sulfuric acid, while for non acid-stable pesticides superposed layers of alumina, silica and florisil impregnated with 15% methanolic solution of KOH were successively used. Recoveries of organochlorine pesticides from certified reference material (CRM 430) were ranging from 86% for p,p'-DDT to 107% for endrin, while recoveries from blank fat spiked fortified at three different levels were between 65% for alachlor at the lowest fortification level and 107% for mirex at the highest fortification level. The limits of detection for each analyte were ranging from 0.1 ng/g to 0.5 ng/g fat. All chlorinated pesticides were found in the analyzed species but at low concentrations. Boulengerochromis microlepis contained the highest concentrations of HCHs (288.2 +/- 15.5 ng/g fat) and DDTs (909.1 +/- 42.5 ng/g fat), while the highest PCB levels (166.7 +/- 37.4 ng/g fat for the sum of 12 congeners) were found in Oreochromis niloticus. However, there is no evidence that Lake Tanganyika is more contaminated with pesticides than other African water bodies. FAU - Manirakiza, P AU - Manirakiza P AD - Toxicological Center, University of Antwerp, Wilrijk, Belgium. manirak@uia.ua.ac.be FAU - Covaci, A AU - Covaci A FAU - Nizigiymana, L AU - Nizigiymana L FAU - Ntakimazi, G AU - Ntakimazi G FAU - Schepens, P AU - Schepens P LA - eng PT - Comparative Study PT - Journal Article PL - England TA - Environ Pollut JT - Environmental pollution (Barking, Essex : 1987) JID - 8804476 RN - 0 (Fats) RN - 0 (Hydrocarbons, Chlorinated) RN - 0 (Pesticides) RN - 0 (Water Pollutants, Chemical) RN - DFC2HB4I0K (Polychlorinated Biphenyls) SB - IM MH - Animals MH - Burundi MH - Chemistry Techniques, Analytical/methods MH - Chromatography, Gas MH - Environmental Monitoring/methods MH - Fats/metabolism MH - Fishes/*metabolism MH - Hydrocarbons, Chlorinated/chemistry/*metabolism MH - Pesticides/chemistry/*metabolism MH - Polychlorinated Biphenyls/chemistry/*metabolism MH - Water Pollutants, Chemical/metabolism MH - Water Pollution, Chemical/analysis EDAT- 2002/03/26 10:00 MHDA- 2002/10/19 04:00 CRDT- 2002/03/26 10:00 PHST- 2002/03/26 10:00 [pubmed] PHST- 2002/10/19 04:00 [medline] PHST- 2002/03/26 10:00 [entrez] AID - S0269-7491(01)00188-9 [pii] AID - 10.1016/s0269-7491(01)00188-9 [doi] PST - ppublish SO - Environ Pollut. 2002;117(3):447-55. doi: 10.1016/s0269-7491(01)00188-9.