PMID- 11915776
OWN - NLM
STAT- MEDLINE
DCOM- 20020910
LR  - 20191105
IS  - 1526-484X (Print)
IS  - 1526-484X (Linking)
VI  - 11
IP  - 4
DP  - 2001 Dec
TI  - Comparison of carbohydrate and milk-based beverages on muscle damage and glycogen 
      following exercise.
PG  - 406-19
AB  - This study examined effects of carbohydrate (CHO), milk-based 
      carbohydrate-protein (CHO-PRO), or placebo (P) beverages on glycogen resynthesis, 
      muscle damage, inflammation, and muscle function following eccentric resistance 
      exercise. Untrained males performed a cycling exercise to reduce muscle glycogen 
      12 hours prior to performance of 100 eccentric quadriceps contractions at 120% of 
      1-RM (day 1) and drank CHO (n = 8), CHO-PRO (n = 9; 5 kcal/kg), or P (n = 9) 
      immediately and 2 hours post-exercise. At 3 hours post-eccentric exercise, serum 
      insulin was four times higher for CHO-PRO and CHO than P (p < .05). Serum 
      creatine kinase (CK) increased for all groups in the 6 hours post-eccentric 
      exercise (p < .01), with the increase tending to be lowest for CHO-PRO (p < .08) 
      during this period. Glycogen was low post-exercise (33+/-3.7 mmol/kg ww), 
      increased 225% at 24 hours, and tripled by 72 hours, with no group differences. 
      The eccentric exercise increased muscle protein breakdown as indicated by urinary 
      3-methylhistidine and increased IL-6 with no effect of beverage. Quadriceps 
      isokinetic peak torque was depressed similarly for all groups by 24% 24 hours 
      post-exercise and remained 21% lower at 72 hours (p < .01). In summary, there 
      were no influences of any post-exercise beverage on muscle glycogen replacement, 
      inflammation, or muscle function.
FAU - Wojcik, J R
AU  - Wojcik JR
AD  - Department of Human Nutrition, Foods, and Exercise at Virginia Polytechnic 
      Institute and State University, Blacksburg 24061, USA.
FAU - Walber-Rankin, J
AU  - Walber-Rankin J
FAU - Smith, L L
AU  - Smith LL
FAU - Gwazdauskas, F C
AU  - Gwazdauskas FC
LA  - eng
PT  - Clinical Trial
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Int J Sport Nutr Exerc Metab
JT  - International journal of sport nutrition and exercise metabolism
JID - 100939812
RN  - 0 (Cytokines)
RN  - 0 (Dietary Carbohydrates)
RN  - 0 (Dietary Proteins)
RN  - 0 (Insulin)
RN  - 0 (Methylhistidines)
RN  - 9005-79-2 (Glycogen)
RN  - EC 2.7.3.2 (Creatine Kinase)
RN  - MEH8O8Y0H0 (3-methylhistidine)
SB  - IM
MH  - Adult
MH  - Animals
MH  - *Beverages
MH  - Creatine Kinase/blood
MH  - Cytokines/blood
MH  - Dietary Carbohydrates/*administration & dosage/metabolism
MH  - Dietary Proteins/*administration & dosage/metabolism
MH  - Exercise/*physiology
MH  - Glycogen/*biosynthesis/metabolism
MH  - Humans
MH  - Insulin/blood
MH  - Kinetics
MH  - Male
MH  - Methylhistidines/urine
MH  - Milk
MH  - Muscle, Skeletal/injuries/*metabolism/pathology
EDAT- 2002/03/28 10:00
MHDA- 2002/09/11 10:01
CRDT- 2002/03/28 10:00
PHST- 2002/03/28 10:00 [pubmed]
PHST- 2002/09/11 10:01 [medline]
PHST- 2002/03/28 10:00 [entrez]
AID - 10.1123/ijsnem.11.4.406 [doi]
PST - ppublish
SO  - Int J Sport Nutr Exerc Metab. 2001 Dec;11(4):406-19. doi: 
      10.1123/ijsnem.11.4.406.