PMID- 11938764
OWN - NLM
STAT- MEDLINE
DCOM- 20020716
LR  - 20061115
IS  - 1000-5625 (Print)
IS  - 1000-5625 (Linking)
VI  - 24
IP  - 2
DP  - 1999
TI  - [Follow-up study of human herpesvirus 6 and human cytomegalovirus infection in 
      organ transplantation recipients].
PG  - 116-8
AB  - OBJECTIVE: To trace the study of the prevalence and adverse factors of human 
      herpesvirus 6(HHV-6) and human cytomegalovirus(HCMV) infection in organ 
      transplantation recipients. METHOD: Blood and urine specimens were detected by 
      virus isolation, polymerase chain reaction(PCR), and indirect immunofluorescent 
      assay. RESULT: HCMV and HHV-6 isolation rate were 25.8% and 32.3%, respectively. 
      Anti-HCMV IgM and anti-HHV-6 IgM positive rates before operation were 0% and 
      3.2%, their positive rates after operation were 19.4% and 25.8%, respectively. 
      HCMV-DNA and HHV-6-DNA positive rates before operation were 35.5% and 45.2%; 
      their positive rates after operation were 45.2% and 61.3%, and kept the high 
      positive rates for a long period. The patients who died within 3 months were all 
      complicated by HCMV and/or HHV-6 productive infection. The productive infection 
      rates of HCMV and HHV-6 were 25.8% and 32.2%, respectively. CONCLUSION: The 
      majority of HCMV and HHV-6 infection are reactivation. Productive infection 
      attack at 2 weeks after operation, reaches the peak at 3-4 weeks after operation, 
      and attacks at anytime within 3 months. HCMV and/or HHV-6 productive infection 
      are fatal to recipients.
FAU - Luo, M
AU  - Luo M
AD  - Department of Microbiology and Immunology, Hunan Medical University, Changsha 
      410078.
FAU - Xiao, Y
AU  - Xiao Y
FAU - Dai, G
AU  - Dai G
LA  - chi
PT  - English Abstract
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - China
TA  - Hunan Yi Ke Da Xue Xue Bao
JT  - Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical 
      University
JID - 9424769
SB  - IM
MH  - *Cytomegalovirus Infections
MH  - Female
MH  - Follow-Up Studies
MH  - Heart Transplantation
MH  - *Herpesviridae Infections
MH  - *Herpesvirus 6, Human
MH  - Humans
MH  - Liver Transplantation
MH  - Lung Transplantation
MH  - Male
MH  - *Organ Transplantation
MH  - Postoperative Complications/*virology
EDAT- 2002/04/10 10:00
MHDA- 2002/07/18 10:01
CRDT- 2002/04/10 10:00
PHST- 2002/04/10 10:00 [pubmed]
PHST- 2002/07/18 10:01 [medline]
PHST- 2002/04/10 10:00 [entrez]
PST - ppublish
SO  - Hunan Yi Ke Da Xue Xue Bao. 1999;24(2):116-8.