PMID- 11948609
OWN - NLM
STAT- MEDLINE
DCOM- 20020705
LR  - 20191025
IS  - 0197-8462 (Print)
IS  - 0197-8462 (Linking)
VI  - 23
IP  - 4
DP  - 2002 May
TI  - 50 Hz magnetic fields of varying flux intensity affect cell shape changes in 
      invertebrate immunocytes: the role of potassium ion channels.
PG  - 292-7
AB  - The effect induced by exposure to 50 Hz magnetic fields (MFs) in immunocytes from 
      the mussel Mytilus galloprovincialis is evaluated. The whole animal was exposed 
      for 15 and 30 min to MF intensities ranging from 200 to 1,000 microT. The changes 
      in the cellular shape of immunocytes, expressed as shape factor (SF), were 
      studied at different times after addition of the chemotacting substance 
      N-formyl-Meth-Leu-Phe (fMLP). Results show that MFs provoke differing delays in 
      fMLP-induced cellular shape changes: 200 microT are ineffective, while levels 
      from 300 microT upwards cause a significant increase in immunocyte SF values 
      compared to controls. Reactivation of the cells is possible up to an intensity of 
      600 microT. The use of PCO 400, an opener of ATP-sensitive K+ channels, shows 
      that potassium channels are involved in the effect of MFs on M. galloprovincialis 
      immunocytes.
CI  - Copyright 2002 Wiley-Liss, Inc.
FAU - Ottaviani, Enzo
AU  - Ottaviani E
AD  - Department of Animal Biology, University of Modena and Reggio Emilia, Italy. 
      ottaviani.enzo@unimo.it
FAU - Malagoli, Davide
AU  - Malagoli D
FAU - Ferrari, Alex
AU  - Ferrari A
FAU - Tagliazucchi, Davide
AU  - Tagliazucchi D
FAU - Conte, Angela
AU  - Conte A
FAU - Gobba, Fabriziomaria
AU  - Gobba F
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Bioelectromagnetics
JT  - Bioelectromagnetics
JID - 8008281
RN  - 0 (Potassium Channels)
RN  - 59880-97-6 (N-Formylmethionine Leucyl-Phenylalanine)
SB  - IM
MH  - Analysis of Variance
MH  - Animals
MH  - Bivalvia/*radiation effects
MH  - Cell Size/*radiation effects
MH  - *Electromagnetic Fields
MH  - Lymphocytes/physiology/*radiation effects
MH  - N-Formylmethionine Leucyl-Phenylalanine/pharmacology
MH  - Potassium Channels/drug effects/*physiology/radiation effects
EDAT- 2002/04/12 10:00
MHDA- 2002/07/06 10:01
CRDT- 2002/04/12 10:00
PHST- 2002/04/12 10:00 [pubmed]
PHST- 2002/07/06 10:01 [medline]
PHST- 2002/04/12 10:00 [entrez]
AID - 10.1002/bem.10021 [pii]
AID - 10.1002/bem.10021 [doi]
PST - ppublish
SO  - Bioelectromagnetics. 2002 May;23(4):292-7. doi: 10.1002/bem.10021.