PMID- 11960958 OWN - NLM STAT- MEDLINE DCOM- 20020621 LR - 20131121 IS - 8750-7587 (Print) IS - 0161-7567 (Linking) VI - 92 IP - 5 DP - 2002 May TI - Metabolic and appetite responses to prolonged walking under three isoenergetic diets. PG - 2061-70 AB - The effects of three isoenergetic diets on metabolic and appetite responses to prolonged intermittent walking were investigated. Eight men undertook three 450-min walks at intensities varying between 25-30 and 50-55% of maximal O2 uptake. In a balanced design, the subjects were given breakfast, snacks, and lunch containing total carbohydrate (CHO), protein (P), and fat (F) in the following amounts (g/70 kg body mass): mixed diet, 302 CHO, 50 P, 84 F; high-CHO diet, 438 CHO, 46 P, 35 F; high-fat diet, 63 CHO, 44 P, 196 F. Substrate balance was calculated by indirect calorimetry over the 450-min exercise period. Blood samples were taken before exercise and every 45 min during the exercise period. The high-fat diet resulted in a negative total CHO balance (-140 +/- 1 g) and a lower negative fat balance (-110 +/- 33 g) than the other two diets (P < 0.05). Plasma glucagon, nonesterified fatty acids, glycerol, and 3-hydroxybutyrate were higher with the high-fat diet (P < 0.05 vs. high CHO), whereas plasma insulin was lower after high fat (P < 0.05 vs. mixed and high CHO). Subjective ratings of fatigue and appetite showed no differences between the three trials. Although diet influenced the degree of total CHO and fat oxidation, fat was the main source of energy in all trials. FAU - Ainslie, P N AU - Ainslie PN AD - Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, L3 2ET, United Kingdom. humpains@livjm.ac.uk FAU - Abbas, K AU - Abbas K FAU - Campbell, I T AU - Campbell IT FAU - Frayn, K N AU - Frayn KN FAU - Harvie, M AU - Harvie M FAU - Keegan, M A AU - Keegan MA FAU - MacLaren, D P M AU - MacLaren DP FAU - Macdonald, I A AU - Macdonald IA FAU - Paramesh, K AU - Paramesh K FAU - Reilly, T AU - Reilly T LA - eng PT - Clinical Trial PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - United States TA - J Appl Physiol (1985) JT - Journal of applied physiology (Bethesda, Md. : 1985) JID - 8502536 RN - 0 (Blood Glucose) RN - 0 (Dietary Carbohydrates) RN - 0 (Dietary Fats) RN - 0 (Fatty Acids, Nonesterified) RN - 0 (Insulin) RN - 0 (Triglycerides) RN - 9007-92-5 (Glucagon) RN - PDC6A3C0OX (Glycerol) RN - TZP1275679 (3-Hydroxybutyric Acid) SB - IM MH - 3-Hydroxybutyric Acid/blood MH - Adult MH - Appetite/*physiology MH - Blood Glucose MH - Calorimetry, Indirect MH - Dietary Carbohydrates/metabolism MH - Dietary Fats/metabolism MH - Energy Intake/*physiology MH - Energy Metabolism/*physiology MH - Fatigue/metabolism MH - Fatty Acids, Nonesterified/blood MH - *Food, Formulated MH - Glucagon/blood MH - Glycerol/blood MH - Heart Rate/physiology MH - Humans MH - Insulin/blood MH - Male MH - Oxidation-Reduction MH - Triglycerides/blood MH - Walking/*physiology EDAT- 2002/04/19 10:00 MHDA- 2002/06/22 10:01 CRDT- 2002/04/19 10:00 PHST- 2002/04/19 10:00 [pubmed] PHST- 2002/06/22 10:01 [medline] PHST- 2002/04/19 10:00 [entrez] AID - 10.1152/japplphysiol.01049.2001 [doi] PST - ppublish SO - J Appl Physiol (1985). 2002 May;92(5):2061-70. doi: 10.1152/japplphysiol.01049.2001.