PMID- 12000501 OWN - NLM STAT- MEDLINE DCOM- 20021115 LR - 20191105 IS - 0905-6157 (Print) IS - 0905-6157 (Linking) VI - 13 IP - 1 DP - 2002 Feb TI - Anaphylactic reaction to lychee in a 12-year-old girl: cross-reactivity to latex? PG - 64-7 AB - There are very few case reports on allergic reactions to lychee in the literature - so far only in adults. We report on a 12-year-old girl who developed swelling of lips, pruritus, generalized urticaria and dyspnea 30 min after eating a raw lychee. A second event occurred after eating a piece of cake covered with a fruit cocktail. All other foods were well tolerated. In infancy the girl had suffered from atopic dermatitis, which disappeared in childhood; for the previous 2 yr she had presented with seasonal allergic rhinoconjunctivitis. Upon oral provocation, she developed restlessness, flush, generalized urticaria and inspiratory stridor 50 min after eating half a lychee. The diagnostic work up showed a clear positive skin prick test to raw lychee and specific immunoglobulin E (IgE) in serum to latex but not to lychee. In the cellular antigen stimulation test (CAST) carried out with lychee extracts in several concentrations, the same positive results could be found confirming an allergic reaction. Cross-reactivity of lychee to latex was shown by inhibition experiments using the UniCAP 100-system. In conclusion, it seems worthwhile considering the rare allergy to lychee in the case of unclear food-allergic reactions and lychee should be added to the list of foods cross-reacting with latex. FAU - Niggemann, B AU - Niggemann B AD - Department of Pediatric Pneumology and Immunology, University Children's Hospital, Charite of Humboldt University, Berlin, Germany. bodo.niggemann@charite.de FAU - Reibel, S AU - Reibel S FAU - Hipler, C AU - Hipler C FAU - Wahn, U AU - Wahn U LA - eng PT - Case Reports PT - Journal Article PL - England TA - Pediatr Allergy Immunol JT - Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology JID - 9106718 SB - IM MH - Anaphylaxis/chemically induced MH - Child MH - Cross Reactions/immunology MH - Female MH - Humans MH - Latex Hypersensitivity/immunology MH - Nut Hypersensitivity/*complications/immunology MH - Skin Tests EDAT- 2002/05/10 10:00 MHDA- 2002/11/26 04:00 CRDT- 2002/05/10 10:00 PHST- 2002/05/10 10:00 [pubmed] PHST- 2002/11/26 04:00 [medline] PHST- 2002/05/10 10:00 [entrez] AID - pai0c032 [pii] AID - 10.1034/j.1399-3038.2002.00032.x [doi] PST - ppublish SO - Pediatr Allergy Immunol. 2002 Feb;13(1):64-7. doi: 10.1034/j.1399-3038.2002.00032.x.