PMID- 12014872
OWN - NLM
STAT- MEDLINE
DCOM- 20020712
LR  - 20041117
IS  - 0009-9260 (Print)
IS  - 0009-9260 (Linking)
VI  - 57
IP  - 4
DP  - 2002 Apr
TI  - Imaging of peripheral PNET: common and uncommon locations.
PG  - 272-7
AB  - AIM: We present the imaging features of peripheral primitive neuroectodermal 
      tumour (PNET) in eight children, highlighting the unusual locations of this 
      tumour in three children. MATERIALS AND METHODS: At presentation, the tumours 
      were studied with magnetic resonance imaging (MRI; n = 6), computed tomography 
      (CT; n = 7) and ultrasound (US; n = 1). The diagnoses were confirmed 
      histologically (n = 8), immunohistochemically (n = 8), by cytogenetics (n = 3) 
      and electron microscopy (n = 1). Correlation with gross pathology, histology, 
      treatment and outcome were obtained. RESULTS: The tumours were located in the 
      chest wall (n = 2), shoulder, pelvis, small bowel mesentery, adrenal gland, dura 
      mater and skin and subcutaneous tissue of the abdominal wall (n = 1 each). 
      Peripheral PNET arising from the small bowel mesentery, adrenal gland and dura 
      mater have not been previously reported in the English literature. The tumours 
      were mainly large (mean size: 10.6 cm) and infiltrative. All tumours were 
      heterogeneously hyperintense on T2-weighted MRI, heterogeneously iso/hypodense on 
      CT and had variable contrast enhancement. Most tumours were heterogeneously 
      hypointense to muscle on T1-weighted MRI. US showed a hypoechoic mass with a 
      cystic component. CONCLUSION: Peripheral PNET can occur in unusual locations. The 
      clinical and imaging features of peripheral PNET are non-specific, making tissue 
      diagnosis essential. PNET should be included in the differential diagnosis of 
      aggressive soft tissue tumours in children.
CI  - Copyright 2002 The Royal College of Radiologists.
FAU - Khong, P L
AU  - Khong PL
AD  - Department of Diagnostic Radiology, The University of Hong Kong, Queen Mary 
      Hospital, Hong Kong. plkhong@hkucc.hku.hk
FAU - Chan, G C F
AU  - Chan GC
FAU - Shek, T W H
AU  - Shek TW
FAU - Tam, P K H
AU  - Tam PK
FAU - Chan, F L
AU  - Chan FL
LA  - eng
PT  - Journal Article
PL  - England
TA  - Clin Radiol
JT  - Clinical radiology
JID - 1306016
SB  - IM
MH  - Adolescent
MH  - Adrenal Gland Neoplasms/diagnosis
MH  - Child
MH  - Child, Preschool
MH  - Dura Mater
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Infant
MH  - Magnetic Resonance Imaging
MH  - Male
MH  - Meningeal Neoplasms/diagnosis
MH  - Mesentery
MH  - Neuroectodermal Tumors, Primitive/*diagnosis
MH  - Peritoneal Neoplasms/diagnosis
MH  - Soft Tissue Neoplasms/*diagnosis
MH  - Tomography, X-Ray Computed
EDAT- 2002/05/17 10:00
MHDA- 2002/07/13 10:01
CRDT- 2002/05/17 10:00
PHST- 2002/05/17 10:00 [pubmed]
PHST- 2002/07/13 10:01 [medline]
PHST- 2002/05/17 10:00 [entrez]
AID - S0009926001908074 [pii]
AID - 10.1053/crad.2001.0807 [doi]
PST - ppublish
SO  - Clin Radiol. 2002 Apr;57(4):272-7. doi: 10.1053/crad.2001.0807.