PMID- 1203396
OWN - NLM
STAT- MEDLINE
DCOM- 19760330
LR  - 20131121
IS  - 0320-9725 (Print)
IS  - 0320-9725 (Linking)
VI  - 40
IP  - 4
DP  - 1975 Jul-Aug
TI  - [Identification of the inhibition type of hexokinase and pyruvate kinase activity 
      by Ca2+].
PG  - 885-9
AB  - Ca2+ inhibitory effect on hexokinase (HK) and pyruvatkinase activities is 
      studied. Kinetic analysis of the inhibition reaction is carried out to determine 
      the inhibition type. Non-competitive inhibition with respect to reaction 
      activator, Mg2+, is found for HK and PK. On the basis of graph analysis data for 
      both reactions the values of the activatory constant (KA) and the inhibitory 
      constant (Ki) are calculated. The experimental results are discussed with respect 
      to possible regulatory effect of Ca2+ on glycolysis cycle.
FAU - Genin, M S
AU  - Genin MS
FAU - Andreev, V S
AU  - Andreev VS
LA  - rus
PT  - English Abstract
PT  - Journal Article
TT  - Identifikatsiia tipa ingibirovaniia ionami Ca2+ aktivnosti geksokinazy i 
      piruvatkinazy.
PL  - Russia (Federation)
TA  - Biokhimiia
JT  - Biokhimiia (Moscow, Russia)
JID - 0372667
RN  - EC 2.7.1.1 (Hexokinase)
RN  - EC 2.7.1.40 (Pyruvate Kinase)
RN  - I38ZP9992A (Magnesium)
RN  - SY7Q814VUP (Calcium)
SB  - IM
MH  - Calcium/*pharmacology/physiology
MH  - Enzyme Activation
MH  - Glycolysis
MH  - Hexokinase/*antagonists & inhibitors
MH  - Kinetics
MH  - Magnesium/pharmacology
MH  - Pyruvate Kinase/*antagonists & inhibitors
EDAT- 1975/07/01 00:00
MHDA- 1975/07/01 00:01
CRDT- 1975/07/01 00:00
PHST- 1975/07/01 00:00 [pubmed]
PHST- 1975/07/01 00:01 [medline]
PHST- 1975/07/01 00:00 [entrez]
PST - ppublish
SO  - Biokhimiia. 1975 Jul-Aug;40(4):885-9.